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PerCP/Cyanine5.5 Anti-Mouse CD45 Antibody [30-F11] (AGEL1674)

SKU:
AGEL1674
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Applications:
FC
Reactivity:
Mouse
Host Species:
Rat
Isotype:
IgG2a,k
Clone:
30-F11
Conjugation:
PerCP/Cy5.5
€179 - €409
Frequently bought together:

Description

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PerCP/Cyanine5.5 Anti-Mouse CD45 Antibody [30-F11]

The Mouse CD45 Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (30-F11, AGEL1674) is a powerful tool for researchers studying immune cell populations in mouse models. This antibody, specifically designed for flow cytometry applications, targets the CD45 antigen, a pan-leukocyte marker found on all white blood cells.With its PerCP-Cyanine5.5 conjugation, this monoclonal antibody offers enhanced sensitivity and versatility in multicolor flow cytometry experiments. The 30-F11 clone used in its development ensures high specificity and reliable results, making it suitable for various research applications.

By accurately detecting and quantifying CD45-expressing cells, this antibody facilitates the identification and characterization of immune cell subsets in tissues and blood samples. Its use can aid in understanding immune responses, investigating diseases, and evaluating the effects of experimental treatments in preclinical research.For researchers seeking to delve deeper into immune system dynamics and leukocyte populations in mouse models, the Mouse CD45 Monoclonal Antibody PerCP-Cyanine5.5 Conjugated (30-F11, AGEL1674) offers a valuable tool for precise and insightful flow cytometry analysis.

Product Title:PerCP/Cyanine5.5 Anti-Mouse CD45 Antibody [30-F11]
SKU:AGEL1674
Size:25µg, 100µg
Clone No:30-F11
Synonyms:Receptor-type tyrosine-protein phosphatase C;Ptprc;L-CA;Ly-5;T200;CD45;
Host Species:Rat
Reactivity:Mouse
Application:FCM
Isotype:Rat IgG2b, κ
Isotype Control:PerCP/Cyanine5.5 Rat IgG2b, κ Isotype Control[LTF-2]
Form:Liquid
Conjugation:PerCP/Cyanine 5.5
Recommended Use:Each lot of this antibody is quality control tested by flow cytometric analysis. Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/106 cells in 100 μL volume].
Spectrum:Spectrum Image
Swissprot:P06800
Gene ID:19264
Storage Buffer:Phosphate buffered solution, pH 7.2, containing 0.09% stabilizer and 1% protein protectant.
Stability & Storage:Keep as concentrated solution. Store at 2~8°C and protected from prolonged exposure to light. Do not freeze. Centrifuge before opening to ensure complete recovery of vial contents. This product is guaranteed up to one year from purchase.
Background:CD45 is a 180-240 kD glycoprotein also known as the leukocyte common antigen (LCA), T200, or Ly-5. It is a member of the protein tyrosine phosphatase (PTP) family, expressed on all hematopoietic cells except mature erythrocytes and platelets. There are different isoforms of CD45 that arise from alternative splicing of exons 4, 5, and 6, which encode A, B, and C determinants, respectively. CD45 plays a key role in TCR and BCR signal transduction. These isoforms are very specific to the activation and maturation state of the cell as well as cell type. The primary ligands for CD45 are galectin-1, CD2, CD3, CD4, TCR, CD22, and Thy-1.

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