IKKε Rabbit Polyclonal Antibody (CAB0244)
- SKU:
- CAB0244
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | IKKε Rabbit Polyclonal Antibody |
SKU: | CAB0244 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 497-716 of human IKKε (NP_054721.1). |
Sequence: | SRLR TLAE VLSR CSQN ITET QESL SSLN RELV KSRD QVHE DRSI QQIQ CCLD KMNF IYKQ FKKS RMRP GLGY NEEQ IHKL DKVN FSHL AKRL LQVF QEEC VQKY QASL VTHG KRMR VVHE TRNH LRLV GCSV AACN TEAQ GVQE SLSK LLEE LSHQ LLQD RAKG AQAS PPPI APYP SPTR KDLL LHMQ ELCE GMKL LASD LLDN NRII ERLN RVPA PPDV |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | IKKE; IKKI; IKK-E; IKK-i; IKKε |
Positive Sample: | SW480,DU145,MCF7,Mouse liver,Mouse spleen,Rat spleen |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Nucleus, PML body. |
Calculated MW: | 80kDa |
Observed MW: | 80kDa/ |
IKBKE is a noncanonical I-kappa-B (see MIM 164008) kinase (IKK) that is essential for regulating antiviral signaling pathways. IKBKE has also been identified as a breast cancer (MIM 114480) oncogene and is amplified and overexpressed in over 30% of breast carcinomas and breast cancer cell lines (Hutti et al., 2009 [PubMed 19481526]).
Purification Method: | Affinity purification |
Gene ID: | 9641 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |