The Hltf Polyclonal Antibody (CAB8353) is a vital tool for researchers studying the Helicase-like Transcription Factor (HLTF), a protein involved in DNA repair and transcription regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity when detecting HLTF in various biological samples, particularly in Western blot applications.HLTF is a key player in maintaining genomic stability and preventing the accumulation of DNA damage, making it a significant target for cancer research and other diseases associated with genetic instability.
By targeting HLTF with this antibody, researchers can gain insights into its role in DNA repair mechanisms and cellular response to genotoxic stress, leading to potential therapeutic strategies for cancer treatment and other genetic disorders.Overall, the Hltf Polyclonal Antibody (CAB8353) is an essential tool for investigating the functions of HLTF in cellular processes and disease pathways, offering valuable insights for advancing our understanding of DNA repair mechanisms and potential therapeutic interventions.
Product Name:
HLTF Rabbit Polyclonal Antibody
SKU:
CAB8353
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 726-1009 of human HLTF (NP_620636.1).
This gene encodes a member of the SWI/SNF family. Members of this family have helicase and ATPase activities and are thought to regulate transcription of certain genes by altering the chromatin structure around those genes. The encoded protein contains a RING finger DNA binding motif. Two transcript variants encoding the same protein have been found for this gene. However, use of an alternative translation start site produces an isoform that is truncated at the N-terminus compared to the full-length protein.
Purification Method:
Affinity purification
Gene ID:
6596
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HLTF antibody (CAB8353) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
