The FTMT Polyclonal Antibody (CAB12867) is a valuable tool for researchers studying FTMT, a key protein involved in iron metabolism and oxidative stress response. This antibody, generated in rabbits, exhibits high reactivity with human samples and is specifically validated for use in immunohistochemistry and ELISA applications. By binding to FTMT, this antibody enables the detection and analysis of the protein in various experimental settings, making it well-suited for investigations in fields such as biochemistry, cell biology, and neurosciences.FTMT, also known as mitochondrial ferritin, is crucial for maintaining iron homeostasis within mitochondria and protecting cells from iron-mediated oxidative damage.
Dysregulation of FTMT has been implicated in various diseases, including neurodegenerative disorders and cancer. By studying the function and regulation of FTMT, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for intervention.Overall, the FTMT Polyclonal Antibody (CAB12867) serves as a valuable tool for researchers looking to explore the roles of FTMT in health and disease, providing a means to deepen our understanding of iron metabolism and oxidative stress pathways.
Product Name:
FTMT Rabbit Polyclonal Antibody
SKU:
CAB12867
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 183-242 of human FTMT (NP_803431.1).
Predicted to enable ferric iron binding activity and ferrous iron binding activity. Involved in several processes, including cellular iron ion homeostasis; positive regulation of aconitate hydratase activity; and positive regulation of succinate dehydrogenase activity. Located in nucleus.
Purification Method:
Affinity purification
Gene ID:
94033
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse testis, using FTMT Rabbit pAb (CAB12867) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
