The EPHA6 Polyclonal Antibody (PAC05626) is a valuable tool for research involving the EPHA6 protein, a member of the Eph receptor family known for its role in mediating cell signaling pathways. This antibody is raised in rabbits and exhibits high reactivity with human samples, making it an excellent choice for Western blot applications. By binding specifically to the EPHA6 protein, this antibody enables accurate detection and analysis in a variety of cell types, making it an ideal option for studies in cell biology and cancer research.EPHA6 is known to be involved in various cellular processes, including cell adhesion, migration, and differentiation.
Its dysregulation has been implicated in cancer progression and metastasis, highlighting its potential as a therapeutic target in cancer treatment. By studying the function of EPHA6 using this antibody, researchers can gain valuable insights into the mechanisms underlying cancer development and potentially identify novel treatment strategies.In summary, the EPHA6 Polyclonal Antibody (PAC05626) is a reliable tool for investigating the role of EPHA6 in cell signaling pathways and cancer biology. Its high reactivity and specificity make it a valuable asset for researchers seeking to unravel the complexities of EPHA6-mediated cellular processes.
Antibody Name:
EPHA6 Antibody (PACO56226)
Antibody SKU:
PACO56226
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
ELISA:1:2000-1:10000, IHC:1:200-1:500
Species Reactivity:
Human
Immunogen:
Recombinant Human Ephrin type-A receptor 6 protein (132-279AA)
IHC image of PACO56226 diluted at 1:200 and staining in paraffin-embedded human heart tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
IHC image of PACO56226 diluted at 1:200 and staining in paraffin-embedded human brain tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0). Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4°C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
Background:
Receptor tyrosine kinase which binds promiscuously GPI-anchored ephrin-A family ligands residing on adjacent cells, leading to contact-dependent bidirectional signaling into neighboring cells. The signaling pathway downstream of the receptor is referred to as forward signaling while the signaling pathway downstream of the ephrin ligand is referred to as reverse signaling (By similarity).
