The DDX24 Polyclonal Antibody (CAB15481) is a valuable tool for researchers studying DDX24, an essential RNA helicase involved in RNA metabolism and gene expression regulation. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By binding to the DDX24 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in molecular biology and gene regulation.DDX24 plays a crucial role in various cellular processes, including RNA splicing, translation, and mRNA decay, making it a key player in gene expression control.
Its involvement in these pathways highlights its importance in understanding fundamental biological mechanisms and its potential as a target for therapeutic interventions in diseases such as cancer and neurodegenerative disorders. Research using the DDX24 Polyclonal Antibody can provide valuable insights into the function and regulation of DDX24, paving the way for advancements in biomedical research and drug development.
Product Name:
DDX24 Rabbit Polyclonal Antibody
SKU:
CAB15481
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 510-859 of human DDX24 (NP_065147.1).
DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which shows little similarity to any of the other known human DEAD box proteins, but shows a high similarity to mouse Ddx24 at the amino acid level.
Purification Method:
Affinity purification
Gene ID:
57062
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using DDX24 Rabbit pAb (CAB15481) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
