COX6A1 Rabbit Polyclonal Antibody (CAB3798)
- SKU:
- CAB3798
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cell Biology
Description
Product Name: | COX6A1 Rabbit Polyclonal Antibody |
SKU: | CAB3798 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 25-109 of human COX6A1 (NP_004364.2). |
Sequence: | SSGA HGEE GSAR MWKT LTFF VALP GVAV SMLN VYLK SHHG EHER PEFI AYPH LRIR TKPF PWGD GNHT LFHN PHVN PLPT GYED E |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 IHC-P,1:20 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | COX6A; CMTRID; COX6AL; COX6A1 |
Positive Sample: | A-549,MCF7,Mouse kidney,Mouse heart,Mouse liver,Rat liver,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion inner membrane. |
Calculated MW: | 12kDa |
Observed MW: | 12kDa |
Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented.
Purification Method: | Affinity purification |
Gene ID: | 1337 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |