Blog
Targeting Immune Checkpoints as Cancer Therapy
In recent years, the field of oncology has witnessed a paradigm shift with the advent of immunotherapy, a treatment modality that harnesses the body's immune system to combat cancer. Among the mos
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16th Feb 2024
STING Activators As Cancer Therapeutics
The STING (Stimulator of Interferon Genes) pathway plays a pivotal role in the innate immune system's response to cancerous cells and DNA viruses. Exploiting this pathway through STING activators
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15th Feb 2024
Unraveling the Synergy: How Growth Factors Cooperate to Promote Tumorigenesis
In the intricate ballet of cellular communication and regulation, growth factors play pivotal roles in guiding the processes of cell growth, division, and differentiation. These proteins are essen
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15th Feb 2024
Deciphering B Cell Cancers With a Rituximab Biosimilar
The fight against B cell cancers, a challenging spectrum of hematologic malignancies, has entered a new era with the introduction of rituximab biosimilars. These biosimilars promise to extend the
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5th Feb 2024
Biomarkers & Inflammatory markers of atherosclerosis
As atherosclerosis is a complex inflammatory disease, there are many influential biomarkers that contribute to the disease’s progression as well as biomarkers from atherosclerosis rela
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23rd Jan 2024
VEGF-A VEGFR-2 Signaling: Decoding the Blueprint of Angiogenesis for Therapeutic Insights
The orchestration of angiogenesis, the process by which new blood vessels form from pre-existing ones, is a complex symphony regulated by various molecular players. At the forefront of this int
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18th Jan 2024
The Role of Tumor Suppressor Genes in Cancer: Knudson Hypothesis & Oncogenes
The focus of this article is Tumor Suppressor Genes. There are various different types of tumor suppressor genes, with BRCA being one of the most popular. The role of Tumor Suppressor Genes in Can
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24th Aug 2023
Antibody Conjugation: Techniques and Applications
Antibody conjugation is a pivotal technique in biomedical research and diagnostic applications. This process involves the covalent attachment of a molecule, such as a drug, toxin, enzym
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24th Aug 2023
Positive Control vs Negative Control
T cell activation is a crucial process in the immune response, playing a pivotal role in how the body responds to pathogens and maintains immune homeostasis. This intricate process involves severa
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24th Aug 2023
Myeloid Lineage: Pioneers of Immune Cell Production
Delve into the myeloid lineage, a cornerstone of the immune system and blood cell production, understanding its vital roles and implications in health and disease. Key Takeaways: Myeloi
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25th Jul 2023
Fibroblast Markers
Fibroblasts, essential components of connective tissues, play vital roles in maintaining tissue structure and function. Their remarkable ability to produce and organize the extracellular matrix
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20th Jul 2023
von Willebrand Factor and Cancer
What is von Willebrand Factor?
Von Willebrand Factor (VWF) is a crucial glycoprotein that plays
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18th Jul 2023
Cancer Metabolism: Tumorigenesis, Metabolic Therapy & The Warburg Effect
Cancer Metabolism is the mechanism by which cancer cells make energy in order for them to grow and spread. Even in the presence of oxygen, cancer cells increase glucose uptake and pr
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14th Jul 2023
What is RNAi? All You Need to Know
RNA interference (RNAi), also referred to as Post-Transcriptional Gene Silencing (PTGS), is the process by which RNA molecules silence genes in response to double-stranded RNA. RNA interference (R
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13th Jul 2023
Mitotic Catastrophe Review
Delving into the intricate world of Mitotic Catastrophe, this blog unveils its critical role in cell division and cancer therapy, offering insights into its mechanisms and potential treatments.
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11th Jul 2023
Cyclins and Cyclin Dependent Kinase – Review
Cyclins and CDKs are central to cell cycle control, with specific cyclin-CDK pairs regulating different phases, ensuring orderly progression and genomic integrity in cell division. Key Takeawa
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10th Jul 2023
The p53 Protein: Tumor Suppressor Protein
p53, encoded by the TP53 gene on chromosome 17, is a fundamental protein safeguarding against tumor formation. It orchestrates cellular responses to DNA damage and stress, crucially managing cell
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5th Jul 2023
Dendritic Cells - Markers, Activation & Subtypes
Exploring the multifaceted role of dendritic cells in immune function and disease. Key Takeaways DCs are professional antigen-presenting cells that capture, process, and prese
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12th Jun 2023
​TNF alpha & Inflammation
Delving into TNF alpha's critical role in inflammation and its therapeutic targeting. Key Takeaways: TNF alpha is a crucial cytokine in inflammation and apoptosis. Its structure facilitat
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8th Jun 2023
The Role of Claudins in Cancer
Introduction
Claudins are a family of proteins that play a critical role in the formation of t
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16th Mar 2023
Ovarian Cancer: Symptoms, Causes, Diagnosis and Treatment
Ovarian cancer is the fourth most common cancer in women. Ovarian cancer is when the normal cells in the ovary change and grow to form a tumour. Because the ovaries are located deep
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3rd Apr 2022
Chronic myelogenous leukaemia (CML) – Review
Chronic myelogenous leukaemia (CML) is a myeloproliferative haematopoietic malignancy, characterised by a karyotypic abnormality present in more than 95% of cases known as the Philadelph
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1st Apr 2022
Leukemia Inhibitory Factor: An Overview
Leukemia Inhibitory Factor and JAK-STAT Signalling Pathway
Leukemia inhibitory factor (LIF) is a cytokine that belongs to the interleukin-6 (IL-6) family of cytokines. Other members of
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24th Mar 2022
Esophageal Cancer: Causes, Symptoms, Diagnosis, Treatment, and Prevention
Esophageal cancer is a type of cancer that affects the esophagus, which is the tube that carries food and liquids from your mouth to your stomach. Esophageal cancer can cause many di
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21st Mar 2022