Blog
Alemtuzumab Biosimilar: Advancing CD52-Targeted Therapy
Alemtuzumab is a monoclonal antibody targeting CD52, a glycoprotein highly expressed on mature lymphocytes. By binding CD52, Alemtuzumab induces immune-mediated depletion of lymphocytes,
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17th Dec 2025
Enavatuzumab Biosimilar: Advancing TWEAKR-Targeted Therapy in Cancer
Enavatuzumab is a monoclonal antibody targeting TWEAK receptor (TWEAKR, also known as Fn14), a member of the tumor necrosis factor receptor (TNFR) family. Overexpressed in many solid tumo
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17th Dec 2025
Vorsetuzumab: Advancing Cancer Research with CD70 Targeting
Vorsetuzumab, a monoclonal antibody targeting CD70, is an investigational therapy designed to treat hematologic malignancies and solid tumors. CD70, a member of the tumor necrosis factor
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28th Dec 2024
Daratumumab: Advancing Research in Multiple Myeloma and Beyond
Daratumumab, a human monoclonal antibody targeting CD38, is a breakthrough therapy for multiple myeloma (MM) and other CD38-expressing hematologic malignancies. It enhances immune-mediate
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28th Dec 2024
Talacotuzumab: Exploring CD123-Targeting Therapies in AML and MDS Research
Talacotuzumab, a humanized monoclonal antibody targeting CD123, has shown promise in treating acute myeloid leukemia (AML) and other hematologic malignancies. As a key immunotherapy, it e
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28th Dec 2024
Elotuzumab: Revolutionizing Multiple Myeloma Treatment and Research Applications
Elotuzumab is a monoclonal antibody that targets SLAMF7 (signaling lymphocytic activation molecule F7), a protein highly expressed on multiple myeloma (MM) cells and natural killer (NK) c
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28th Dec 2024
Rituximab Biosimilar: Transforming CD20-Targeted Therapy for Hematologic Malignancies
Rituximab is a monoclonal antibody targeting CD20, a cell surface protein found on B lymphocytes. By engaging immune-mediated mechanisms, Rituximab eliminates CD20-positive B cells, makin
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12th Dec 2024
Tiragolumab Biosimilar: Enhancing Immune Checkpoint Therapy with TIGIT Inhibition
Tiragolumab is a monoclonal antibody targeting TIGIT (T-cell immunoglobulin and ITIM domain), an immune checkpoint receptor that suppresses T-cell and natural killer (NK) cell activity in
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12th Dec 2024
Vibostolimab Biosimilar: Advancing Immune Activation with TIGIT Inhibition
Vibostolimab is a monoclonal antibody that targets TIGIT (T-cell immunoglobulin and ITIM domain), an immune checkpoint receptor that suppresses T-cell and natural killer (NK) cell activit
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12th Dec 2024
Belantamab Biosimilar: Targeting BCMA for Multiple Myeloma Treatment
Belantamab mafodotin is an antibody-drug conjugate (ADC) targeting B-cell maturation antigen (BCMA), a protein highly expressed on malignant plasma cells in multiple myeloma (MM). By deli
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12th Dec 2024
Pinatuzumab Biosimilar: Advancing CD22-Targeted Therapy in B-Cell Malignancies
Pinatuzumab vedotin is an antibody-drug conjugate (ADC) targeting CD22, a cell surface marker highly expressed on malignant B cells. It delivers a potent cytotoxic agent directly to CD22-
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12th Dec 2024
Etigilimab Biosimilar: Advancing TIGIT Inhibition in Cancer Immunotherapy
Etigilimab is a monoclonal antibody targeting TIGIT (T-cell immunoglobulin and ITIM domain), an immune checkpoint receptor that suppresses T-cell activity in tumors. By blocking TIGIT, Et
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10th Dec 2024
Girentuximab Biosimilar: Targeting Carbonic Anhydrase IX (CAIX) for Cancer Therapy
Girentuximab is a monoclonal antibody targeting carbonic anhydrase IX (CAIX), a tumor-associated antigen overexpressed in clear cell renal cell carcinoma (ccRCC) and hypoxic tumors. By se
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10th Dec 2024
Tesnatilimab Biosimilar: Advancing CD38-Targeted Therapy
Tesnatilimab is a monoclonal antibody targeting CD38, a transmembrane glycoprotein highly expressed on malignant plasma cells in multiple myeloma (MM) and other hematologic malignancies.
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10th Dec 2024
Sacituzumab Biosimilar: Advancing Trop-2-Targeted Cancer Therapy
Sacituzumab govitecan is an innovative antibody-drug conjugate (ADC) targeting Trop-2, a transmembrane glycoprotein overexpressed in many epithelial cancers. By selectively delivering a c
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10th Dec 2024
Ipilimumab Biosimilar: Expanding Access to CTLA-4 Inhibition
Ipilimumab (Yervoy) is a monoclonal antibody targeting cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), a key immune checkpoint receptor. By inhibiting CTLA-4, Ipilimumab enhances T-
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9th Dec 2024
Amatuximab Biosimilar: Advancing Mesothelin-Targeted Therapy for Cancer
Amatuximab is a monoclonal antibody targeting mesothelin, a tumor-associated antigen overexpressed in several aggressive cancers, including mesothelioma and pancreatic cancer. By binding
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8th Dec 2024
Iscalimab Biosimilar: Advancing CD40-Targeted Therapy for Immune Modulation
Iscalimab (CFZ533) is a monoclonal antibody targeting CD40, a key receptor in the immune system. By blocking CD40-CD40L interactions, Iscalimab inhibits immune activation, making it a pro
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7th Dec 2024
Ifabotuzumab Biosimilar: Advancing EGFRvIII-Targeted Cancer Therapy
Ifabotuzumab is a monoclonal antibody targeting the EGFRvIII mutation, a tumor-specific variant of the epidermal growth factor receptor (EGFR). This mutation is associated with aggressive
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7th Dec 2024
Varlilumab Biosimilar: Enhancing Immune Activation via CD27-Targeted Therapy
Varlilumab is a monoclonal antibody targeting CD27, a critical costimulatory receptor in the immune system. Acting as a CD27 agonist, Varlilumab enhances T-cell activation and effector fu
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5th Dec 2024
Brentuximab Biosimilar: Advancing CD30-Targeted Therapy
Brentuximab vedotin is a CD30-targeting antibody-drug conjugate (ADC) approved for treating CD30-positive malignancies, such as Hodgkin lymphoma (HL) and anaplastic large cell lymphoma (A
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5th Dec 2024
Biosimilar: Expanding Access to Monoclonal Antibody-Based Therapies
1. What is a Biosimilar? A biosimilar is a biologic medical product that is highly similar to an already-approved reference biologic. While minor differences in clinically inactive c
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5th Dec 2024
Gemtuzumab Biosimilar: Advancing CD33-Targeted Therapy for AML
Gemtuzumab ozogamicin is a CD33-targeting antibody-drug conjugate (ADC) approved for the treatment of acute myeloid leukemia (AML). By selectively delivering a cytotoxic payload to CD33-p
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5th Dec 2024
Indatuximab Biosimilar: A New Frontier in CD138-Targeted Cancer Therapy
Indatuximab ravtansine is a CD138-targeting antibody-drug conjugate (ADC) designed for the treatment of multiple myeloma and other CD138-expressing cancers. By delivering a cytotoxic payl
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4th Dec 2024