Blog
ILC2: The Immune Cell That Fights Allergies and Infections
ILC2 - Function, Cytokines, and Role in Health and Disease
A quick guide to IL2C
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25th Jan 2023
NLRP3 Inflammasome & Cytokine Secretion
Nod-like receptors
Nod like receptors (NLRs) are a versatile family of relatively recently discovered intracellular receptors which have a br
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23rd May 2022
T Cell Types, Activation, Polarization & Function
T Cell Types, Activation, Polarization & Function A comprehensive guide to T cells!
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12th Apr 2022
Mouse Monoclonal Antibody
Mouse monoclonal antibodies are a valuable tool in the biomedical field. They can be used for a variety of applications, from research to clinical diagnostics. In this blog post, we
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4th Mar 2022
CD52 Expression
What is CD52?
Cluster Of Differentiation 52 (CD52) is a highly expressed membrane glycoprotein which is present on the surface of immune cell
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15th Feb 2022
CD31: A Comprehensive Look at an Essential Biomarker
What is CD31?
CD31, also known as PECAM-1, was originally described as a cell surface antigen present on platelets and megakaryocytes. CD31 is
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15th Feb 2022
What are MHC Class I and II molecules?
What are MHC Class I molecules? The MHC class I is a glycoprotein that is expressed on all nucleated cells of the human body. MHC class I are important in disease defense against viruses, ba
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18th Jan 2022
How do antibodies work?
Antibodies are a special class of Y shaped proteins that help guard your body from invading viruses and bacteria. They do this by either neutralizing the dangerous
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17th Jan 2022
What is an Antigen?
Antigen's are foreign molecules recognised by the immune system.
Antigens can be protein, carbohydrate, lipid or nucleic acid molecules.
Examples include viruses and bacteria as
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15th Jan 2022
chemokine receptors and ligands
Chemokines are highly conserved cytokines that control the movement of cells around the body. All 45 members of the chemokine family can be divided into 4 subfamilies depending on th
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1st Dec 2021
ST2 and IL33
ST2, a member of the IL-1R Subfamily
ST2 is a member of the IL-1R subfamily and was identified in 1989 [1]. The ST2 gene is located on chromoso
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7th Oct 2021
Data Science for Immunologists | Assay Genie
By Dr. Niclas Thomas
“Data science” is a recent addition to the vocabulary of analytics, and can mean many different things to different people. As fa
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20th Aug 2021
Immuno-Biomaterial Development | Assay Genie
Background
I am a 3rd year PhD student in Trinity College Dublin and my project is very much an interdisciplinary one. I’m very lucky to get to work between two great labs, Dr. Aisling Dunn
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20th Aug 2021
microbiota & immune system signaling | Assay Genie
You are only part human.
In some ways, you are as much bacteria as you are mammal, and in some ways bacteria make up far more of you than your own familiar cells and genes!
It is becoming
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20th Aug 2021
Cells of the Immune System | Assay Genie
The Immune System
The immune system is a host defence system comprising many biological structures and processes within an organism that prot
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19th Aug 2021
The Complement System - pathways & function in the immune system
The Complement System Function
Gone are the days when the complement system was considered solely a companion of its impressive adaptive immune system counte
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9th Mar 2021
Neutrophils - Cells of the Immune System
The immune system is the body’s main defence against infection. In order to function properly, the immune system must be able to detect and protect against infinite agents su
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8th Mar 2021
Carbon Dioxide sensing in Immune Cells
BRIEF HISTORY OF THE “GREEN” EVOLUTION OF OXYGEN AND CARBON DIOXIDE WITHIN OUR ATMOSPHERE
Million years ago carbon dioxide (CO2) levels used to be conside
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8th Mar 2021
How we can target the underlying immune processes in pathological inflammation in obesity, cancer and liver disease.
Dr. Melissa Conroy, TTMI
I am an immunologist and senior research fellow in the Cancer Immunology and Immunotherapy Group, Department of Surgery at Trinity
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8th Mar 2021
SOCS proteins: Manipulating the immune response
Katherine Edwards, PhD Student, Queen’s University Belfast
Cytokines play a vital role in immune responses enabling cross-talk between different cell types a
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8th Mar 2021
Trauma Immunology
Traumatic injuries & death
When I ask people what the leading cause of death is in the United States in people age 44 and under, they generally reply saying
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8th Mar 2021
The Influence of dietary interventions upon platelet reactivity
Laura Menke PhD candidate, Queen Mary University of London
Inflammation vs. Resolution
Atherothrombosis is the leading cause of death worldwide
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8th Mar 2021
Interferons
Interferons (IFNs) are a group of signalling proteins that are produced and released from cells in response to viral infection and other stimuli such as normal and tumour cell surviv
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6th Mar 2021
The IL-36 Subfamily | Expression, Function & Regulation
By Charlotte O'Donnell PhD
The genes of the IL-36 family members are located in a cluster on chromosome 2 [1]. All three activating ligands, IL-36α, IL-36β a
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1st Jan 1970