Blog
Histamine Receptors: Gatekeepers of Immunological and Neurological Responses
Histamine, a biogenic amine, plays a crucial role in various physiological processes, including immune responses, gastric acid secretion, and neurotransmission. Central to the action of histamine
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15th Mar 2024
Decoding Parkinson's Disease: Insights into a Complex Neurological Disorder
Parkinson's disease (PD) is a progressive neurological disorder that primarily affects the motor system, leading to a wide array of symptoms ranging from tremors and stiffness to bradykinesia (slo
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16th Feb 2024
Understanding Glutamate Receptors: Classification, Function, and Implications in Neurological Disorders
Glutamate receptors are pivotal in mediating excitatory neurotransmission in the central nervous system (CNS), playing crucial roles in synaptic transmission, plasticity, learning, and memory. The
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16th Feb 2024
Ionotropic Glutamate Receptors: Gateways to Neural Communication
Ionotropic glutamate receptors (iGluRs) are pivotal in the fast excitatory synaptic transmission in the mammalian central nervous system (CNS). These receptors are not only crucial for normal brai
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13th Feb 2024
Understanding Parkinson's Disease: Insights and Innovations
Parkinson's disease (PD) is a progressive neurological disorder that predominantly affects the motor system, leading to a wide range of symptoms including tremors, rigidity, bradykinesia (slownes
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8th Feb 2024
Alzheimer's Disease: A Comprehensive Insight
Alzheimer's disease stands as a formidable challenge in the realm of neurological disorders, characterized by its progressive nature and profound impact on cognitive functions. This article delve
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7th Feb 2024
Neural Stem Cell Differentiation: Pathways and Lineage-Specific Markers
Understanding the differentiation pathways of neural stem cells (NSCs) and the identification of lineage-specific markers is a cornerstone in the field of neurobiology and regenerative medicine. T
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26th Jan 2024
Understanding the Gut-Brain Axis
The gut-brain axis, a dynamic bi-directional communication system linking
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24th Aug 2023
Neurofilament Light chain (NEFL) as a biomarker for neuronal damage
Delve into the pivotal role of Neurofilament Light chain (NEFL) in neuron structure and its emerging importance as a biomarker for various neurodegenerative diseases, offering insights into dis
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24th Aug 2023
Schwann Cells: Specialized Cells that Support Nerve Function
Schwann cells are cells that play a vital role in nerve function. They are responsible for myelinating axons and helping to ensure the transmission of electrical signals between neurons. Schwann c
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20th Jul 2023
A Quick Guide to Myelin
The myelin sheath is an insulating layer around nerve cells. It is made up of a substance called myelin, which is produced by special cells called oligodendrocytes. Myelin protects the nerve cells
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19th Jul 2023
Astrocyte Markers: A Guide
Explore the world of astrocytes, crucial star-shaped cells in the brain, and understand how specific markers help study their roles in neural health and disorders. Key Takeaways: Ast
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25th Jun 2023
Oligodendrocytes: What Are They?
Oligodendrocytes are pivotal CNS cells, integral for myelin formation and nerve function, with implications in various neurological disorders. Key Takeaways Oligodendrocytes are specia
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22nd Jun 2023
Understanding Radial Glial Cells: Insights into Neurodevelopmental Processes
Radial glial cells are essential in shaping the nervous system, serving dual roles in neurogenesis and structural support during the brain's developmental stages. Key Takeaways: Radi
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21st Jun 2023
A Guide To Tau Proteins & Tauopathies
Explore the essential role of Tau proteins in neuronal health and their impact in neurodegenerative diseases, unfolding the complexity behind their functions and dysfunctions. Key Takeaways:
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21st Jun 2023
The Functions of Microglial Cells & Their Role in Neurodegenerative Disorders
Key Takeaways: Microglia are immune cells in the CNS, originating from myeloid precursor cells. They surveil the CNS, respond to changes, and maintain neural health. Microglia exist in diff
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18th Jun 2023
Tau proteins: An Overview
The tau protein is a hot topic in the scientific world right now. This little-known protein has been linked to Alzheimer's disease, Parkinson's disease, and other neurodegenerative disea
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27th Mar 2022
The Blood Brain Barrier: An Overview
What is the blood-brain barrier?
The Blood-brain barrier (BBB) is a system of vessels that acts as a structural and chemical barrier between the brain and the rest of the body's circula
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24th Mar 2022
How do Neurons work?
A neuron is a cell that processes and transmits information through electrical and chemical signals. There are trillions of them in the human brain, which is able to carry out so many complex
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15th Jan 2022
Types of Glial Cells
Microglia
Astrocytes
Oligodendrocytes
Glial
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14th Jan 2022
Toll-like Receptor Signalling in Neurodegenerative Disease
Toll-Like Receptors
The innate immune response has come under the spotlight in recent years due to its central role in propagating the pathogen
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7th Oct 2021
BDNF in inflammation and neuropathologies
BDNF Overview
Brain-derived neurotrophic factor (BDNF) is a central mediator of neuroplasticity, a term used to describe the ability of neurons
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6th Oct 2021
From Stem Cells To Neurons: A Cnidarian Approach
By Eleni Chrysostomou, PhD Candidate, NUIG
Why do we need to know how the Nervous System develops and regenerates?
The structure and function of
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11th Mar 2021
The Ubiquitin Proteasome System in Neurodegenerative disease
By Sinead Kinsella PhD
The Ubiquitin Proteasome System (UPS)
The Ubiquitin Proteasome System (UPS) is a regulatory machinery for protein turnover in t
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10th Mar 2021