Blog
Oct-4 Stem Cells
Oct-4 stem cells, also known as Octamer-binding transcription factor 4 stem cells, are a fascinating area of study in the field of stem cell research. These stem cells hold great promise du
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12th Jun 2023
Understanding Phosphorylation: From ATP Synthesis to Cellular Signaling
Introduction Phosphorylation is a fundamental biochemical process that plays a crucial role in various cellular functions. It involves the addition of a phosphate group to a molecule, typi
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11th Jun 2023
The Blood Coagulation Pathway and related Disorders
Blood Coagulation Pathways Blood clotting, also known as hemostasis, is a fascinating and intricate process that ensures our bodies can effectively respond to injuries and prevent excessive
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8th Jun 2023
An Insight Into Necrosis- Causative Effects And Methods Of Prevention
What is Necrosis? Necrosis is a pathological process characterized by the death of cells or tissues within a living organism. It occurs as a result of various factors, including injury, infe
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8th Jun 2023
Understanding Bone Resorption: Key Definitions and Processes
Unravel the complexities of bone resorption, a crucial biological process essential for skeletal health and calcium regulation, through the intricate roles of osteoclasts and osteoblasts. Ke
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29th May 2023
Beta Oxidation of Fatty Acids
Understanding Beta-Oxidation: A Comprehensive Overview Fatty acids provide a highly efficient energy storage mechanism, delivering more energy per gram than common carbohydrates like gluc
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28th May 2023
Flow Cytometry Protocol | 10 Hints & Tips
Flow Cytometry Protocol
The meaning is in the name:
Flow = in motion, Cyto = cells, Metry = measure.
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7th Nov 2022
Guide to Fluorescence Activated Cell Sorting (FACs): The Latest Technology in Cell Separation
Fluorescence activated cell sorting (FACS) is a cutting-edge technique used to isolate individual cells from a sample and analyse their properties. In this guide, we will discuss the basics
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26th Jul 2022
Protein Kinases: Overview, Classification and Therapeutic Potential
Kinases, key enzymes in cellular signaling, phosphorylate proteins to regulate crucial processes, and their modulation has significant implications in disease treatment. Key Takeaways: Ki
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13th Jun 2022
Spindle Assembly Checkpoint review
Spindle assembly checkpoint
The spindle assembly checkpoint (SAC), or mitotic checkpoint, is the main cell cycle control mechanism that governs mitosis. Incorrec
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26th Apr 2022
The Exciting Field of Stem Cell Research
What are Stem Cells?
Stem cells are primitive, undifferentiated, and unspecialised cells that are found in multicellular organisms
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21st Jan 2022
Inflammation and the aging process
by Ryan Wallis, PhD
Aging and Disease
Imagine a world where everything you do is missing just a little piece and as time goes on you start to lose sense entirely.
This is the deva
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20th Jan 2022
CRISPR-Cas Screening for Cell Viability
Key Points
Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is a method of gene editing that uses t
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28th Sep 2021
RIPA Buffer Recipe - Cell Lysis | Assay Genie
RIPA (Radio Immuno Precipitation Assay) buffer is mostly used when carrying out a western blot or immunoprecipatation assay. A RIPA buffer is used in order to lyse cells and extract protein fro
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20th Aug 2021
Bone Morphogenetic Proteins (BMP) – Review
Bone Morphogenetic Proteins (BMP) were first discovered in the 1960s by Dr.Marshall Urist, an orthopaedic surgeon at UCLA (Urist 1965). BMPs are classically associated with their roles in limb
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11th Mar 2021
Follicle Stem Cell Behaviour
David Melamed, Phd Candidate, Colombia University
When I started in the Kalderon Lab five years ago, I had no idea that our work would lead us to drastical
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11th Mar 2021
Cytokinesis review
By John Bannon PhD
Early Cytokinesis
Early cytokinesis; from anaphase to midbody formation cytokinesis is the physical s
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11th Mar 2021
Polo-like kinase (Plk1) substrates and mitosis
Polo-like kinase (Plk1)
Polo-like kinase (Plk1), is a serine/threonine kinase that is active during mitosis (Hamanaka et al., 1995). Its name is derived from its origi
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10th Mar 2021
A broccoli juice a day keep the heart attack away
Alex Lloyd PhD Candidate, Dublin Institute of Technology
Did you know that roughly 17.5 million people worldwide die annually from Cardiovascular diseases
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10th Mar 2021
Do you know…migraines affect more than 10% of the world population?
By Francisco Algaba Chueco
In this post we discuss a topic that everyone will have heard of. Let’s talk about migraines, a disorder that hides a huge ph
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10th Mar 2021
Metabolism or pluripotency – which regulates which? A chicken or the egg story.
By Sophie Arthur
How many diseases and conditions do you think exist in this world? Thousands? Hundreds of thousands? Maybe even millions? Unfortunately, I don’t know the answer. But what I
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10th Mar 2021
Investigating orthohantavirus infections with proteomics
Sarah Brun Bar-Yaacov PhD Candidate, University of Liverpool
Orthohantaviruses are a group of segmented negative-sense RNA viruses maintained as asympto
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10th Mar 2021
An insight into the topology of the Enteric Nervous System
The Enteric Nervous system (ENS) is one of the largest subdivisions of the Peripheral Nervous System. This remarkable system is embedded between sheets of smooth muscle cells of the intestinal
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10th Mar 2021
Sensing Danger: The Biology of TLR-Mediated Inflammation
By Eoin Mac Réamoinn
Toll-like receptors (TLRs) are renowned for their fundamental roles in innate sensing and initiating inflammatory responses. TLRs
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8th Mar 2021