Blog
Unlocking Cellular Adaptation: The HIF Enhancer Pathway and Its Implications in Hypoxia Response
Hypoxia, or low oxygen levels, poses a significant challenge to cells, necessitating rapid and efficient adaptation mechanisms. The Hypoxia-Inducible Factor (HIF) pathway is a well-known regula
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12th Jan 2024
Exploring Organelle Markers: Illuminating the Cellular Landscape
The eukaryotic cell is a complex and dynamic system with distinct membrane-bound compartments known as organelles, each performing specialized functions essential for cellular survival. To better
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11th Jan 2024
Understanding the mTOR Signaling Pathway: A Key Player in Cell Growth and Metabolism
The mammalian target of rapamycin (mTOR) signaling pathway is a crucial regulator of cell growth and metabolism, responding to environmental cues and cellular energy status. This pathway's signifi
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5th Jan 2024
MAPK Signaling: Unraveling the Pathway of Mitogen Stimulation
Introduction to MAPK Signaling in Cellular Processes Mitogen-Activated Protein Kinase (MAPK) signaling pathways are crucial in transmitting signals from the cell surface to the DNA in the ce
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5th Jan 2024
Deciphering the Intricacies of TGF-Beta Signaling Pathway
Transforming Growth Factor-Beta (TGF-β) signaling pathway plays a pivotal role in orchestrating various cellular processes, ranging from embryonic development to tissue homeostasis and immune
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24th Aug 2023
The Role of Tumor Suppressor Genes in Cancer: Knudson Hypothesis & Oncogenes
The focus of this article is Tumor Suppressor Genes. There are various different types of tumor suppressor genes, with BRCA being one of the most popular. The role of Tumor Suppressor Genes in Can
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24th Aug 2023
Antibody Conjugation: Techniques and Applications
Antibody conjugation is a pivotal technique in biomedical research and diagnostic applications. This process involves the covalent attachment of a molecule, such as a drug, toxin, enzym
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24th Aug 2023
Positive Control vs Negative Control
T cell activation is a crucial process in the immune response, playing a pivotal role in how the body responds to pathogens and maintains immune homeostasis. This intricate process involves severa
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24th Aug 2023
A Comprehensive Overview of Cell Death
Cell death is an essential aspect of cellular biology that plays a crucial
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23rd Aug 2023
Immunophenotyping by Flow Cytometry and Cell Type Markers
Immunophenotyping by Flow Cytometry Immunophenotyping is a technique used in the field of immunology and cell biology to identify and classify cells based on the specific proteins o
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23rd Aug 2023
Oxidative Stress: Causes, Biomarkers & Disease
Oxidative Stress Definition
Oxidative stress is a condition that results when the body produces or consumes more reactive oxygen
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23rd Aug 2023
Autophagy in Focus: Molecular Mechanisms and Functional Insights
Autophagy, a fundamental cellular process, plays an indispensable role in maintaining cellular home
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15th Aug 2023
Cellular Respiration
Discover the intricacies of cellular respiration, a critical process for energy production in cells, encompassing aerobic and anaerobic pathways and their molecular mechanisms Key Takeaways
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24th Jul 2023
A Quick Guide to Myelin
The myelin sheath is an insulating layer around nerve cells. It is made up of a substance called myelin, which is produced by special cells called oligodendrocytes. Myelin protects the nerve cells
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19th Jul 2023
Converting RPM to G-force in Centrifugation
Centrifuges play a pivotal role in scientific research and various industr
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19th Jul 2023
What is RNAi? All You Need to Know
RNA interference (RNAi), also referred to as Post-Transcriptional Gene Silencing (PTGS), is the process by which RNA molecules silence genes in response to double-stranded RNA. RNA interference (R
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13th Jul 2023
Cyclins and Cyclin Dependent Kinase – Review
Cyclins and CDKs are central to cell cycle control, with specific cyclin-CDK pairs regulating different phases, ensuring orderly progression and genomic integrity in cell division. Key Takeawa
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10th Jul 2023
Immunometabolism – A therapeutic perspective
What is Immunometabolism?
Immunometabolism is an exponentially growing, multi-disci
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10th Jul 2023
Pyruvate dehydrogenase (PDH)
Pyruvate dehydrogenase is a complex enzyme involved in the conversion of p
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7th Jul 2023
Alternative Complement Pathway: Activation, Regulation, and Significance
As a vital component of the immune system, the Alternative Complement Pathway plays a crucial role in defending the body against pathogens and maintaining immune homeostasis. In this blog, we w
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5th Jul 2023
Microtubule and Mitosis review
Introduction Microtubules are key components of the cytoskeleton and are composed of alpha and beta tubulin. These dimerise in a head to tail fashion to form 13 linear protofilaments.
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29th Jun 2023
The Essential Guide to DNA: Components, Purpose and Purification Methods
Exploring DNA's essence, this guide illuminates its structure, function, and purification techniques, essential in fields like medicine and biotechnology. Key Takeaways: DNA's Struct
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28th Jun 2023
Transformation Protocol – Sample Transformation Protocols
Introduction Transformation of bacteria with plasmids is not only of note for bacterial studies but also can be used for gene expression studies in mammalian cells. Most plasmids are of bact
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27th Jun 2023
Understanding Radial Glial Cells: Insights into Neurodevelopmental Processes
Radial glial cells are essential in shaping the nervous system, serving dual roles in neurogenesis and structural support during the brain's developmental stages. Key Takeaways: Radi
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21st Jun 2023