Blog
Tigatuzumab Biosimilar: Harnessing DR5 for Targeted Cancer Therapy
Tigatuzumab is a monoclonal antibody targeting death receptor 5 (DR5), a member of the tumor necrosis factor receptor (TNFR) superfamily. By activating DR5, Tigatuzumab induces apoptosis
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17th Dec 2025
Enavatuzumab Biosimilar: Advancing TWEAKR-Targeted Therapy in Cancer
Enavatuzumab is a monoclonal antibody targeting TWEAK receptor (TWEAKR, also known as Fn14), a member of the tumor necrosis factor receptor (TNFR) family. Overexpressed in many solid tumo
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17th Dec 2025
Sacituzumab: Exploring its Role in Cancer Research and the Rise of Biosimilars
Sacituzumab govitecan is an innovative antibody-drug conjugate (ADC) targeting Trop-2, a transmembrane glycoprotein overexpressed in many epithelial cancers. By selectively delivering a c
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2nd Jan 2025
Ipilimumab and Nivolumab: Advancing Research on CTLA-4 in Cancer Therapy
What You Need to Know About IpilimumabWhat is Ipilimumab?Ipilimumab is a monoclonal antibody that targets CTLA-4, a protein involved in downregulating the immune system, to boost the bod
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1st Jan 2025
Ifabotuzumab: Exploring the Role of Anti-EphA3 in Cancer Research
Ifabotuzumab is a monoclonal antibody targeting the EGFRvIII mutation, a tumor-specific variant of the epidermal growth factor receptor (EGFR). This mutation is associated with aggressive
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31st Dec 2024
Brentuximab: Unveiling the Role of Anti-CD30 in Cancer Research
Brentuximab vedotin is a CD30-targeting antibody-drug conjugate (ADC) approved for treating CD30-positive malignancies, such as Hodgkin lymphoma (HL) and anaplastic large cell lymphoma (A
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31st Dec 2024
Gemtuzumab: Advancing CD33-Targeted Therapies in AML Research
Gemtuzumab ozogamicin is a CD33-targeting antibody-drug conjugate (ADC) approved for the treatment of acute myeloid leukemia (AML). By selectively delivering a cytotoxic payload to CD33-p
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31st Dec 2024
Indatuximab: Advancing CD138-Targeted Therapy in Cancer Research
Indatuximab ravtansine is a CD138-targeting antibody-drug conjugate (ADC) designed for the treatment of multiple myeloma and other CD138-expressing cancers. By delivering a cytotoxic payl
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31st Dec 2024
Vopratelimab: Unlocking the Potential of ICOS in Cancer Research
Vopratelimab is a monoclonal antibody targeting inducible T-cell costimulator (ICOS), a key receptor involved in T-cell activation and immune regulation. By selectively activating ICOS, V
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31st Dec 2024
Targeting IL-10R: Enhancing Immune Activation in Cancer
Introduction to IL-10R and Immune Suppression in CancerThe interleukin-10 receptor (IL-10R) is a key player in regulating immune responses, particularly in suppressing inflammation and ma
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12th Dec 2024
Rituximab Biosimilar: Transforming CD20-Targeted Therapy for Hematologic Malignancies
Rituximab is a monoclonal antibody targeting CD20, a cell surface protein found on B lymphocytes. By engaging immune-mediated mechanisms, Rituximab eliminates CD20-positive B cells, makin
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12th Dec 2024
Tiragolumab Biosimilar: Enhancing Immune Checkpoint Therapy with TIGIT Inhibition
Tiragolumab is a monoclonal antibody targeting TIGIT (T-cell immunoglobulin and ITIM domain), an immune checkpoint receptor that suppresses T-cell and natural killer (NK) cell activity in
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12th Dec 2024
Vibostolimab Biosimilar: Advancing Immune Activation with TIGIT Inhibition
Vibostolimab is a monoclonal antibody that targets TIGIT (T-cell immunoglobulin and ITIM domain), an immune checkpoint receptor that suppresses T-cell and natural killer (NK) cell activit
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12th Dec 2024
Pinatuzumab Biosimilar: Advancing CD22-Targeted Therapy in B-Cell Malignancies
Pinatuzumab vedotin is an antibody-drug conjugate (ADC) targeting CD22, a cell surface marker highly expressed on malignant B cells. It delivers a potent cytotoxic agent directly to CD22-
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12th Dec 2024
Girentuximab Biosimilar: Targeting Carbonic Anhydrase IX (CAIX) for Cancer Therapy
Girentuximab is a monoclonal antibody targeting carbonic anhydrase IX (CAIX), a tumor-associated antigen overexpressed in clear cell renal cell carcinoma (ccRCC) and hypoxic tumors. By se
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10th Dec 2024
Tesnatilimab Biosimilar: Advancing CD38-Targeted Therapy
Tesnatilimab is a monoclonal antibody targeting CD38, a transmembrane glycoprotein highly expressed on malignant plasma cells in multiple myeloma (MM) and other hematologic malignancies.
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10th Dec 2024
Ipilimumab Biosimilar: Expanding Access to CTLA-4 Inhibition
Ipilimumab (Yervoy) is a monoclonal antibody targeting cytotoxic T-lymphocyte-associated protein 4 (CTLA-4), a key immune checkpoint receptor. By inhibiting CTLA-4, Ipilimumab enhances T-
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9th Dec 2024
Vorsetuzumab: Advancing Cancer Research with CD70 Targeting
What You Need to Know About VorsetuzumabWhat is Vorsetuzumab?Vorsetuzumab is a monoclonal antibody targeting CD70, a protein found in various cancers. It shows promise for advancing canc
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27th Nov 2024
Talacotuzumab: Exploring CD123-Targeting Therapies in AML and MDS Research
Key Facts About TalacotuzumabWhat is Talacotuzumab?Talacotuzumab is a monoclonal antibody designed to target CD123, a protein commonly found on the surface of certain blood cancer cells.
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27th Nov 2024
Magrolimab: Unveiling the Role of Anti-CD47 in Cancer Research and Beyond
What You Need to Know About MagrolimabWhat is Magrolimab?Magrolimab is an anti-CD47 monoclonal antibody that targets the "don't eat me" signal on cancer cells, promoting their destructio
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27th Nov 2024
Elotuzumab: Revolutionizing Multiple Myeloma Treatment and Research Applications
Quick Facts About ElotuzumabWhat is Elotuzumab?Elotuzumab is a monoclonal antibody designed to enhance the immune system's ability to detect and destroy multiple myeloma cells. It target
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26th Nov 2024
Enoblituzumab: Unveiling the Role of Anti-B7-H3 in Cancer Research
Key Facts About EnoblituzumabWhat is Enoblituzumab?Enoblituzumab is a monoclonal antibody targeting the B7-H3 protein, which is expressed on the surface of various cancer cells, includin
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26th Nov 2024
Atezolizumab: Unveiling the Role of Anti-PD-L1 in Cancer Research
Quick Facts About AtezolizumabWhat is Atezolizumab?Atezolizumab is an anti-PD-L1 monoclonal antibody used in immunotherapy to treat various cancers by enhancing the immune system's abili
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26th Nov 2024
Cobolimab: Unveiling TIM-3’s Role in Cancer Immunotherapy
Quick Facts About CobolimabWhat is Cobolimab?Cobolimab is a monoclonal antibody that targets TIM-3, a checkpoint protein involved in immune regulation, especially in cancer and autoimmun
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26th Nov 2024