Blog
Androgenic steroid action in breast cancer
By Rachel Bleach, PhD Student, RCSI
By the age of 79 years, 1 in 14 women will develop breast cancer (Global Burden of Disease Cancer 2017). Beatson reported
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9th Mar 2021
LATS1/2 Kinases Review
LATS kinases belong to a family of proteins that, in mammals, are comprised of two isoforms, LATS1 and LATS2. Originally identified in Drosophila melanogaster as Warts kinase, LATS1 and LATS2 se
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11th Jan 2021
Cancer & Tumour Suppressors – Mini Review
Cancer DevelopmentCancer is a group of diseases that involves abnormal cell growth resulting in malignant tumours/ malignant neoplasms. Cancer is a leading cause of morbidity, with 14 million ne
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18th Dec 2020
Ras signaling pathway
A wide variety of cell surface receptors activate Ras GTPase, including the tyrosine receptor linked to the epidermal growth factor receptor (EGFR) (Wells 1999). Upon receptor stimulation, son o
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18th Dec 2020
Inhibiting cell division
Unregulated cell growthCancer, although heterogeneous by its very nature, can be broadly defined as a set of diseases characterised by unregulated cell growth leading to invasion of surrounding
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18th Dec 2020
Early Diagnosis is key: Pick the weed or allow it destroy the garden?
By CatrÃona Dowling, Post-Doc, RCSI
I want you to come on a journey with me where we are going to the botanic gardens. You will pick a section of the garden that is yours: yours to treasure
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18th Dec 2020
Cancer Research Club March 2020
ELISA Genie is delighted to announce the date of our next Cancer Research Club which will be taking place on the 31st of March at TTMI, Trinity College Dublin. This event will focu
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16th Dec 2020
Hepatocellular Carcinoma - Methyltransferase expression
Hepatocellular carcinoma (HCC) is one of the most frequently occurring cancers and there are 630,000 new cases diagnosed every year worldwide (De Minicis et al. 2013). HCC develops frequently fr
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1st Jan 1970
Colorectal Cancer Review (CRC) - Assay Genie
By Charlotte O’Donnell PhD
Cancer
Carcinogenesis is a multi-step process that develops through epigenetic changes and
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1st Jan 1970
Liposomal nanosilver encapsulation for cytotoxic assays
Nanosilver is the most commercialised nanoparticle routinely used for its antibacterial purposes in food preservation, cosmetic and health products such as medical devices and wound treatmen
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1st Jan 1970
Pathological functions of IL-33/ST2 in IBD and Cancer
By Charlotte O'Donnell PhD
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1st Jan 1970
Tumour Inflammation & Signaling | Assay Genie
By Charlotte O’Donnell PhD
Inflammation and Cancer
The link between inflammation and cancer is well established, with infl
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1st Jan 1970