Blog
Pembrolizumab: Unveiling Its Mechanism and Research Applications with Biosimilars
Key Facts: PembrolizumabIs Pembrolizumab Safe?Pembrolizumab is widely recognized as safe for most patients, with side effects ranging from mild to severe. Commonly reported side effects
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26th Nov 2024
Daratumumab: Advancing Research in Multiple Myeloma and Beyond
Key Facts About DaratumumabWhat is Daratumumab?Daratumumab is a monoclonal antibody that targets CD38, a protein highly expressed on the surface of multiple myeloma cells.How does Daratu
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26th Nov 2024
Non-Small Cell Lung Carcinoma: Understanding, Diagnosing, and Treating NSCLC
Non-Small Cell Lung Carcinoma (NSCLC) is the most common type of lung cancer, representing about 85% of all lung cancer cases. NSCLC includes several subtypes, with distinct biological ch
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14th Nov 2024
Renal Cell Carcinoma: Understanding, Diagnosing, and Treating Kidney Cancer
Renal Cell Carcinoma (RCC) is the most common form of kidney cancer, originating in the lining of the proximal renal tubules. RCC accounts for approximately 90% of all kidney cancers and
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12th Nov 2024
Melanoma: Understanding, Diagnosing, and Treating Skin Cancer
Melanoma is an aggressive type of skin cancer that originates in melanocytes, the cells responsible for producing melanin, which gives skin its color. Although it is less common than othe
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12th Nov 2024
TREM2: Exploring Its Role in Tumor-Associated Macrophages and Cancer Immunotherapy
Introduction to TREM2 and Tumor-Associated Macrophages in CancerTREM2 (triggering receptor expressed on myeloid cells 2) is an immunoregulatory receptor primarily expressed on macrophages
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31st Oct 2024
FoxP3: Understanding Regulatory T Cell Control in Tumor Immunity
Introduction to FoxP3 and Regulatory T Cells in CancerFoxP3 (forkhead box P3) is a transcription factor critical for the development and function of regulatory T cells (Tregs), a speciali
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30th Oct 2024
CD155: Breaking Immune Suppression in Tumor Environments
Introduction to CD155 in Cancer ImmunotherapyCD155, also known as Poliovirus Receptor (PVR), is a transmembrane protein that plays a pivotal role in tumor immune evasion. While CD155 is n
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29th Oct 2024
TNFRSF9: Enhancing Immune Cell Activity Against Tumors
Introduction to TNFRSF9 and Its Role in Immune ActivationTNFRSF9, also known as 4-1BB or CD137, is a co-stimulatory receptor expressed on the surface of T cells, natural killer (NK) cells
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29th Oct 2024
Dual PD-1/PD-L2 Blockade: Expanding the Horizons of Cancer Immunotherapy
Introduction to PD-1, PD-L1, and PD-L2 in Cancer ImmunotherapyThe PD-1/PD-L1 immune checkpoint pathway has been instrumental in cancer immunotherapy, with PD-1 (programmed death-1) inhibi
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29th Oct 2024
CD86: Enhancing T Cell Activation in Immunotherapy
Introduction to CD86 and Its Role in Immune Activation CD86 is a crucial co-stimulatory molecule that plays an essential role in T cell activation, driving the immune system’s abilit
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23rd Oct 2024
CD80: Amplifying Immune Activation Through Co-Stimulatory Pathways
Introduction to CD80 and Its Role in Immune Activation CD80 is a critical immune checkpoint molecule that plays an essential role in T cell activation through co-stimulatory pathways
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23rd Oct 2024
TLR4: Unraveling the Role of Inflammation in Cancer Progression
Introduction to TLR4 and Cancer Toll-like receptor 4 (TLR4) is a key component of the innate immune system, primarily responsible for detecting infections and initiating inflammatory
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22nd Oct 2024
CD73: Combating Tumor Immunosuppression by Targeting Adenosine
Introduction to CD73 and Tumor Immunosuppression CD73, also known as ecto-5'-nucleotidase, is an enzyme found on the surface of various cells, including tumor cells and immune cells.
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21st Oct 2024
CD39: A Novel Target to Overcome Immunosuppression in Cancer
Introduction to CD39 and Cancer Immunosuppression CD39 is an ectonucleotidase enzyme that plays a crucial role in generating adenosine, a powerful immunosuppressive molecule within t
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21st Oct 2024
SLAMF7: Activating Natural Killer Cells for Potent Anti-Cancer Responses
Introduction to SLAMF7 in Cancer Immunotherapy SLAMF7, also known as Signaling Lymphocytic Activation Molecule F7, is a surface receptor found on natural killer (NK) cells, T cells,
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16th Oct 2024
BTLA: A Key Player in Immune Regulation and Cancer Therapy
Introduction to BTLA in Immune Regulation B and T lymphocyte attenuator (BTLA) is an immune checkpoint molecule that plays a critical role in regulating immune responses by suppressi
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16th Oct 2024
CD122: Fine-Tuning T Cell Responses in Immunotherapy
Introduction to CD122 in Immunotherapy CD122, also known as the interleukin-2 receptor beta chain (IL-2Rβ), is a critical component of the immune system's response to pathogens and m
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15th Oct 2024
TNFR2: Taming Regulatory T Cells to Enhance Anti-Tumor Immunity
In recent years, cancer immunotherapy has become a powerful tool for treating various malignancies. One promising approach involves targeting the tumor microenvironment, particularly regu
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14th Oct 2024
CD27 Activation: Strengthening the Immune Army Against Cancer
Harnessing the immune system to fight cancer has become a pivotal strategy in modern oncology. A key component in this fight is CD27, a receptor that plays a crucial role in T-cell activa
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14th Oct 2024
B7-H4: A New Frontier in Immune Checkpoint Inhibition
The recent advances in cancer immunotherapy have brought new opportunities to harness the body’s immune system against tumors. Among these advancements is the targeting of immune checkpoi
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14th Oct 2024
LILT: A Novel Immune Checkpoint for Cancer Therapy
Recent advances in immunotherapy have highlighted the importance of targeting immune checkpoints to enhance the immune system’s ability to combat cancer. A new potential target in this gr
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14th Oct 2024
ICOS: Stimulating the Immune System for Superior Cancer Therapy
Immunotherapy has transformed the landscape of cancer treatment by leveraging the body’s immune system to target and destroy cancer cells. A key player in this process is Inducible T-cell
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14th Oct 2024
PVR: Balancing Immune Activation and Suppression in Cancer
PVR (Poliovirus receptor), also known as CD155, is a molecule that plays a dual role in regulating the immune response within the tumor microenvironment. While initially discovered as a r
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10th Oct 2024