Blog
FoxP3: Understanding Regulatory T Cell Control in Tumor Immunity
Introduction to FoxP3 and Regulatory T Cells in CancerFoxP3 (forkhead box P3) is a transcription factor critical for the development and function of regulatory T cells (Tregs), a special
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30th Oct 2024
CD155: Breaking Immune Suppression in Tumor Environments
Introduction to CD155 in Cancer ImmunotherapyCD155, also known as Poliovirus Receptor (PVR), is a transmembrane protein that plays a pivotal role in tumor immune evasion. While CD155 is
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29th Oct 2024
TNFRSF9: Enhancing Immune Cell Activity Against Tumors
Introduction to TNFRSF9 and Its Role in Immune ActivationTNFRSF9, also known as 4-1BB or CD137, is a co-stimulatory receptor expressed on the surface of T cells, natural killer (NK) cell
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29th Oct 2024
Dual PD-1/PD-L2 Blockade: Expanding the Horizons of Cancer Immunotherapy
Introduction to PD-1, PD-L1, and PD-L2 in Cancer ImmunotherapyThe PD-1/PD-L1 immune checkpoint pathway has been instrumental in cancer immunotherapy, with PD-1 (programmed death-1) inhib
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29th Oct 2024
CD86: Enhancing T Cell Activation in Immunotherapy
Introduction to CD86 and Its Role in Immune Activation CD86 is a crucial co-stimulatory molecule that plays an essential role in T cell activation, driving the immune system’s abili
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23rd Oct 2024
CD80: Amplifying Immune Activation Through Co-Stimulatory Pathways
Introduction to CD80 and Its Role in Immune Activation CD80 is a critical immune checkpoint molecule that plays an essential role in T cell activation through co-stimulatory pathway
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23rd Oct 2024
TLR4: Unraveling the Role of Inflammation in Cancer Progression
Introduction to TLR4 and Cancer Toll-like receptor 4 (TLR4) is a key component of the innate immune system, primarily responsible for detecting infections and initiating inflammator
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22nd Oct 2024
CD73: Combating Tumor Immunosuppression by Targeting Adenosine
Introduction to CD73 and Tumor Immunosuppression CD73, also known as ecto-5'-nucleotidase, is an enzyme found on the surface of various cells, including tumor cells and immune cells
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21st Oct 2024
CD39: A Novel Target to Overcome Immunosuppression in Cancer
Introduction to CD39 and Cancer Immunosuppression CD39 is an ectonucleotidase enzyme that plays a crucial role in generating adenosine, a powerful immunosuppressive molecule within
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21st Oct 2024
Targeting IL-10R: Enhancing Immune Activation in Cancer
Introduction to IL-10R and Immune Suppression in CancerThe interleukin-10 receptor (IL-10R) is a key player in regulating immune responses, particularly in suppressing inflammation and m
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21st Oct 2024
SLAMF7: Activating Natural Killer Cells for Potent Anti-Cancer Responses
Introduction to SLAMF7 in Cancer Immunotherapy SLAMF7, also known as Signaling Lymphocytic Activation Molecule F7, is a surface receptor found on natural killer (NK) cells, T cells,
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16th Oct 2024
BTLA: A Key Player in Immune Regulation and Cancer Therapy
Introduction to BTLA in Immune Regulation B and T lymphocyte attenuator (BTLA) is an immune checkpoint molecule that plays a critical role in regulating immune responses by suppress
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16th Oct 2024
KIR Blockade: Empowering NK Cells for Superior Tumor Clearance
Introduction to KIR Blockade in Cancer ImmunotherapyNatural killer (NK) cells are crucial components of the innate immune system, responsible for recognizing and destroying virally infec
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15th Oct 2024
CD122: Fine-Tuning T Cell Responses in Immunotherapy
Introduction to CD122 in Immunotherapy CD122, also known as the interleukin-2 receptor beta chain (IL-2Rβ), is a critical component of the immune system's response to pathogens and
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15th Oct 2024
TNFR2: Taming Regulatory T Cells to Enhance Anti-Tumor Immunity
In recent years, cancer immunotherapy has become a powerful tool for treating various malignancies. One promising approach involves targeting the tumor microenvironment, particularly reg
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14th Oct 2024
LILT: A Novel Immune Checkpoint for Cancer Therapy
Recent advances in immunotherapy have highlighted the importance of targeting immune checkpoints to enhance the immune system’s ability to combat cancer. A new potential target in this g
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14th Oct 2024
B7-H4: A New Frontier in Immune Checkpoint Inhibition
The recent advances in cancer immunotherapy have brought new opportunities to harness the body’s immune system against tumors. Among these advancements is the targeting of immune checkpo
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14th Oct 2024
CD27 Activation: Strengthening the Immune Army Against Cancer
Harnessing the immune system to fight cancer has become a pivotal strategy in modern oncology. A key component in this fight is CD27, a receptor that plays a crucial role in T-cell activ
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14th Oct 2024
ICOS: Stimulating the Immune System for Superior Cancer Therapy
Immunotherapy has transformed the landscape of cancer treatment by leveraging the body’s immune system to target and destroy cancer cells. A key player in this process is Inducible T-cel
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14th Oct 2024
CD28: Amplifying T Cell Responses for Better Tumor Clearance
The CD28 molecule plays a crucial role in amplifying T cell activation, which is critical for mounting effective immune responses against tumors. By engaging with co-stimulatory molecule
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10th Oct 2024
PVR: Balancing Immune Activation and Suppression in Cancer
PVR (Poliovirus receptor), also known as CD155, is a molecule that plays a dual role in regulating the immune response within the tumor microenvironment. While initially discovered as a
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10th Oct 2024
CD47: Overcoming Tumor Evasion Through Macrophage Activation
One of the greatest challenges in cancer therapy is how tumors evade immune detection. Among the mechanisms cancer cells exploit, the CD47 pathway has emerged as a major player in helpin
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8th Oct 2024
4-1BB: Energizing Immune Cells to Overcome Tumor Resistance
Immunotherapy has become a central pillar in the fight against cancer, with a focus on enhancing the body’s natural defenses. Among the molecules at the forefront of immunotherapeutic re
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8th Oct 2024
Targeting CD200: Unlocking Immune Suppression in Tumors
Immune evasion is one of the hallmarks of cancer, where tumor cells employ various strategies to suppress immune responses and prevent destruction by the body’s defense systems. CD200, a
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8th Oct 2024