ZFX Rabbit Polyclonal Antibody (CAB16444)
- SKU:
- CAB16444
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Description
Product Name: | ZFX Rabbit Polyclonal Antibody |
SKU: | CAB16444 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 180-380 of human ZFX (NP_003401.2). |
Sequence: | VLVA DCAS EAVI DANG IPVD QQDD DKGN CEDY LMIS LDDA GKIE HDGS SGMT MDTE SEID PCKV DGTC PEVI KVYI FKAD PGED DLGG TVDI VESE PEND HGVE LLDQ NSSI RVPR EKMV YMTV NDSQ PEDE DLNV AEIA DEVY MEVI VGEE DAAA AAAA AAVH EQQM DDNE IKTF MPIA WAAA YGNN SDGI ENRN GTAS A |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | ZNF926; ZFX |
Positive Sample: | H460,HL-60,Mouse testis,Mouse lung,Mouse spleen,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 91kDa |
Observed MW: | 110kDa |
This gene on the X chromosome is structurally similar to a related gene on the Y chromosome. It encodes a member of the krueppel C2H2-type zinc-finger protein family. The full-length protein contains an acidic transcriptional activation domain (AD), a nuclear localization sequence (NLS) and a DNA binding domain (DBD) consisting of 13 C2H2-type zinc fingers. Studies in mouse embryonic and adult hematopoietic stem cells showed that this gene was required as a transcriptional regulator for self-renewal of both stem cell types, but it was dispensable for growth and differentiation of their progeny. Multiple alternatively spliced transcript variants encoding different isoforms have been identified, but the full-length nature of some variants has not been determined.
Purification Method: | Affinity purification |
Gene ID: | 7543 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |