Description
WNT3A Monoclonal Antibody [P3A6AT] (CPAB0562)
The Wnt3a Polyclonal Antibody (CPAB0562) is a valuable tool for researchers studying the Wnt signaling pathway, which plays a crucial role in development, tissue regeneration, and disease progression. This antibody, produced in rabbits, is highly specific for human samples and has been validated for use in Western blot applications.Wnt3a is a member of the Wnt family of proteins, known for their ability to regulate cell proliferation, differentiation, and migration. Aberrant Wnt signaling has been implicated in various diseases, including cancer, neurodegenerative disorders, and developmental abnormalities.
The Wnt3a antibody binds specifically to the Wnt3a protein, allowing for accurate detection and analysis in a variety of cell types.By understanding the role of Wnt3a in cellular processes, researchers can gain insights into the mechanisms underlying disease pathogenesis and potentially identify new therapeutic targets. The Wnt3a Polyclonal Antibody is a valuable tool for advancing research in fields such as oncology, developmental biology, and regenerative medicine.
Product Name: | WNT3A Antibody |
Product Sku: | CPAB0562 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human WNT3A mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human WNT3A amino acids 19-352 purified from Ecoli. |
Clone: | P3A6AT. |
Reactivity: | Other bodies |
Applications: | Western Blot, ELISA, Immunohistochemistry |
Purification Method: | WNT3A antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2a |
Background: | The WNT gene family consists of structurally related genes that encode secreted signaling proteins. These proteins are implicated in oncogenesis and in several developmental processes, including regulation of cell fate and patterning during embryogenesis. WNT3A is a member of the WNT gene family. WNT3A is a protein which shows 96% amino acid identity to mouse Wnt3A protein, and 84% to human WNT3 protein, another WNT gene product. The WNT3A gene is clustered with WNT14 gene, another family member, in chromosome 1q42 region. |
Synonyms: | Protein Wnt-3a, MGC119418, MGC119419, MGC119420, WNT3A, wingless-type MMTV integration site family member 3A. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |