WDR11 Rabbit Polyclonal Antibody (CAB10590)
- SKU:
- CAB10590
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | WDR11 Rabbit Polyclonal Antibody |
SKU: | CAB10590 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 975-1224 of human WDR11 (NP_060587.8). |
Sequence: | YFQK FQLE RVNL QEVK RSTY DHTR KCTD QLLL LGQT DRAV QLLL ETSA DNQH YYCD SLKA CLVT TVTS SGPS QSTI KLVA TNMI ANGK LAEG VQLL CLID KAAD ACRY LQTY GEWN RAAW LAKV RLNP EECA DVLR RWVD HLCS PQVN QKSK ALLV LLSL GCFF SVAE TLHS MRYF DRAA LFVE ACLK YGAF EVTE DTEK LITA IYAD YARS LKNL GFKQ GAVL FASK AGAA GKDL LNEL ESPK EEPI EE |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:2000 |
Synonyms: | DR11; HH14; SRI1; BRWD2; WDR15; WDR11 |
Positive Sample: | DU145,HL-60,HepG2 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Membrane, Nucleus, Single-pass membrane protein. |
Calculated MW: | 137kDa |
Observed MW: | 130kDa |
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
Purification Method: | Affinity purification |
Gene ID: | 55717 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |