The WDR11 Polyclonal Antibody (CAB10590) offered by Assay Genie is a valuable tool for researchers studying the WDR11 protein. This antibody is raised in rabbits and has been validated for use in a variety of applications, including Western blotting and immunofluorescence. It specifically recognizes the WDR11 protein, allowing for accurate detection and analysis in different cell types.WDR11 is a multifunctional protein involved in various cellular processes, including gene expression regulation and cell cycle progression. Research has shown that WDR11 plays a role in developmental processes and is associated with certain genetic disorders.
Studying the function of WDR11 can provide insight into its role in disease development and progression, making this antibody a valuable asset for scientists studying developmental biology and genetic disorders.Overall, the WDR11 Polyclonal Antibody from Assay Genie is a reliable tool for researchers looking to investigate the function of WDR11 in different cellular contexts. Its high reactivity and specificity make it an essential component for studies exploring the role of WDR11 in development, disease, and beyond.
Product Name:
WDR11 Rabbit Polyclonal Antibody
SKU:
CAB10590
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 975-1224 of human WDR11 (NP_060587.8).
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene is located in the chromosome 10q25-26 region, which is frequently deleted in gliomas and tumors of other tissues, and is disrupted by the t(10;19) translocation rearrangement in glioblastoma cells. The gene location suggests that it is a candidate gene for the tumor suppressor locus.
Purification Method:
Affinity purification
Gene ID:
55717
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using WDR11 antibody (CAB10590) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.