The VSNL1 Polyclonal Antibody (CAB6999) is a valuable tool for researchers studying VSNL1, a protein involved in various cellular processes such as neuronal development, synaptic plasticity, and neurodegenerative diseases. This antibody, raised in rabbits, specifically targets VSNL1 in human samples and is validated for use in Western blot applications.VSNL1, also known as Visinin-like 1, is a calcium-binding protein that plays a crucial role in neuronal signaling and function. Dysregulation of VSNL1 has been linked to conditions such as Alzheimer's disease, schizophrenia, and bipolar disorder. By utilizing the VSNL1 Polyclonal Antibody, researchers can effectively detect and analyze VSNL1 in different cell types, providing valuable insights into its role in neurobiology and potential implications for neurological disorders.
The VSNL1 Polyclonal Antibody is a powerful tool for investigating the functions and mechanisms of VSNL1 in both normal and diseased states. Its high specificity and reactivity make it an essential component for studies aimed at understanding the complex roles of VSNL1 in the nervous system, offering potential avenues for therapeutic interventions in neurological conditions.
Product Name:
VSNL1 Rabbit Polyclonal Antibody
SKU:
CAB6999
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 2-191 of human VSNL1/VILIP-1 (NP_003376.2).
This gene is a member of the visinin/recoverin subfamily of neuronal calcium sensor proteins. The encoded protein is strongly expressed in granule cells of the cerebellum where it associates with membranes in a calcium-dependent manner and modulates intracellular signaling pathways of the central nervous system by directly or indirectly regulating the activity of adenylyl cyclase. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Purification Method:
Affinity purification
Gene ID:
7447
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse brain, using VSNL1/VILIP-1 antibody (CAB6999) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
