The USP19 Polyclonal Antibody (CAB9723) is a valuable tool for researchers studying USP19, a ubiquitin-specific protease involved in protein degradation and regulation. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for use in Western blot applications. By targeting the USP19 protein, this antibody allows for the detection and analysis of USP19 expression in various cell types, making it an ideal choice for studies in molecular biology and cell signaling pathways.
USP19 is a key player in the cellular machinery responsible for maintaining protein homeostasis and regulating various biological processes. Its involvement in protein degradation pathways makes it a potential target for therapeutic interventions in diseases such as cancer, neurodegenerative disorders, and metabolic conditions. By unraveling the molecular mechanisms associated with USP19, researchers can gain insights into disease mechanisms and identify potential drug targets for future therapeutic development.
Product Name:
USP19 Rabbit Polyclonal Antibody
SKU:
CAB9723
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human USP19 (NP_001186089.1).
Protein ubiquitination controls many intracellular processes, including cell cycle progression, transcriptional activation, and signal transduction. This dynamic process, involving ubiquitin conjugating enzymes and deubiquitinating enzymes, adds and removes ubiquitin. Deubiquitinating enzymes are cysteine proteases that specifically cleave ubiquitin from ubiquitin-conjugated protein substrates. This protein is a ubiquitin protein ligase and plays a role in muscle wasting. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10869
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using USP19 Rabbit pAb (CAB9723) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
