UBQLN1 Rabbit Polyclonal Antibody (CAB15439)
- SKU:
- CAB15439
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Autophagy
Frequently bought together:
Description
Product Name: | UBQLN1 Rabbit Polyclonal Antibody |
SKU: | CAB15439 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 480-540 of human UBQLN1 (NP_038466.2). |
Sequence: | LIPG FTPG LGAL GSTG GSSG TNGS NATP SENT SPTA GTTE PGHQ QFIQ QMLQ ALAG VNPQ L |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:200 - 1:2000 |
Synonyms: | DA41; DSK2; UBQN; XDRP1; PLIC-1; UBQLN1 |
Positive Sample: | Mouse liver,Rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Cell membrane, Cytoplasm, Cytoplasmic vesicle, Endoplasmic reticulum, Nucleus, autophagosome. |
Calculated MW: | 63kDa |
Observed MW: | 70kDa |
This gene encodes an ubiquitin-like protein (ubiquilin) that shares a high degree of similarity with related products in yeast, rat and frog. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and thus are thought to functionally link the ubiquitination machinery to the proteasome to affect in vivo protein degradation. This ubiquilin has also been shown to modulate accumulation of presenilin proteins, and it is found in lesions associated with Alzheimer's and Parkinson's disease. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 29979 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |