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UBE2C Polyclonal Antibody (CAB21347)

SKU:
CAB21347
$155
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Description

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Product Name:UBE2C Polyclonal Antibody
SKU:CAB21347
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant Protein corresponding to a sequence within amino acids 1-179 of human UBE2C (NP_008950.1).
Sequence:MASQ NRDP AATS VAAA RKGA EPSG GAAR GPVG KRLQ QELM TLMM SGDK GISA FPES DNLF KWVG TIHG AAGT VYED LRYK LSLE FPSG YPYN APTV KFLT PCYH PNVD TQGN ICLD ILKE KWSA LYDV RTIL LSIQ SLLG EPNI DSPL NTHA AELW KNPT AFKK YLQE TYSK QVTS QEP
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:UBCH10; dJ447F3.2; UBE2C
Positive Sample:THP-1,SW620,SK-OV-3
Conjugate:Unconjugated
Cellular Localization:cytosol, nucleoplasm, nucleus, plasma membrane
Calculated MW:20kDa
Observed MW:18kDa

The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, ubiquitin-conjugating enzymes, and ubiquitin-protein ligases. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. The encoded protein is required for the destruction of mitotic cyclins and for cell cycle progression, and may be involved in cancer progression. Multiple transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene have been defined on chromosomes 4, 14, 15, 18, and 19.

Purification Method:Affinity purification
Gene ID:11065
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Product ImageWestern blot analysis of various lysates using UBE2C Rabbit pAb (CAB21347) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates / proteins: 25 μg per lane.Blocking buffer: 3 % nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.

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