TYMS Monoclonal Antibody [PAT1S5AT] (CPAB0092)
- SKU:
- CPAB0092
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PAT1S5AT
- Applications:
- WB
- IF
- ELISA
Frequently bought together:
Description
system_update_alt Datasheet
Product Name: | TYMS Antibody |
Product Sku: | CPAB0092 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human TYMS mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TYMS amino acids 1-313 purified from Ecoli. |
Clone: | PAT1S5AT. |
Reactivity: | Human |
Applications: | Western Blot, Immunofluorescence, ELISA |
Purification Method: | TYMS antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2b |
Background: | Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate as a cofactor which maintains the dTMP (thymidine-5-prime monophosphate) pool vital for DNA replication and repair. Thymidylate synthase plays an important role as a cancer chemotherapeutic agent. Thymidylate synthase is the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and several folate analogs. |
Synonyms: | TMS, EC 2.1.1.45, HST422, Thymidylate synthase, TSase, TS, TYMS, MGC88736. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |