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TYMS Monoclonal Antibody [PAT1S5AT] (CPAB0092)

SKU:
CPAB0092
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1S5AT
Applications:
WB
IF
ELISA
€149
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Description

system_update_alt Datasheet

TYMS Monoclonal Antibody [PAT1S5AT] (CPAB0092)

The TYMS Polyclonal Antibody (CPAB0092) is a valuable tool for researchers studying thymidylate synthase (TYMS), an enzyme involved in DNA synthesis and repair. This antibody, raised in rabbits, is highly specific to TYMS and is validated for use in various applications, including Western blotting.TYMS plays a crucial role in cell proliferation and is often overexpressed in cancer cells, making it a potential target for cancer therapies. By detecting and analyzing TYMS expression levels in different cell types, researchers can gain insights into its role in cancer development and progression.

Additionally, the TYMS Polyclonal Antibody can be used in studies related to drug resistance, as TYMS is a target for certain chemotherapy agents. Understanding the regulation and activity of TYMS can provide valuable information for improving the efficacy of cancer treatments and developing new therapeutic strategies.Overall, the TYMS Polyclonal Antibody is a valuable tool for researchers interested in studying the biological functions of TYMS and its potential implications in cancer biology and drug resistance mechanisms.

Product Name:TYMS Antibody
Product Sku:CPAB0092
Size:5μg
Host Species:Mouse
Immunogen:Anti-human TYMS mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human TYMS amino acids 1-313 purified from Ecoli.
Clone:PAT1S5AT.
Reactivity:Human
Applications:Western Blot, Immunofluorescence, ELISA
Purification Method:TYMS antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:Thymidylate synthase catalyzes the methylation of deoxyuridylate to deoxythymidylate using 5,10-methylenetetrahydrofolate as a cofactor which maintains the dTMP (thymidine-5-prime monophosphate) pool vital for DNA replication and repair. Thymidylate synthase plays an important role as a cancer chemotherapeutic agent. Thymidylate synthase is the primary site of action for 5-fluorouracil, 5-fluoro-2-prime-deoxyuridine, and several folate analogs.
Synonyms:TMS, EC 2.1.1.45, HST422, Thymidylate synthase, TSase, TS, TYMS, MGC88736.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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