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TUBB2B Antibody (PACO12986)

SKU:
PACO12986
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€669

Description

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TUBB2B Antibody (PACO12986)

The TUBB2B Polyclonal Antibody (PAC012986) is a valuable tool for researchers studying TUBB2B, a member of the tubulin protein family involved in microtubule dynamics. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the TUBB2B protein, this antibody enables accurate detection and analysis in various cell types, making it an excellent choice for investigations in cell biology and cancer research.TUBB2B plays a crucial role in cell division, intracellular transport, and cell shape maintenance, making it an important target for studies on cellular processes and diseases such as cancer.

As microtubules are involved in various cellular functions, understanding the role of TUBB2B is essential for gaining insights into cell biology and developing potential therapies targeting microtubule dynamics. This antibody provides researchers with a reliable tool to explore the functions and mechanisms of TUBB2B in physiological and pathological conditions.

Antibody Name:TUBB2B Antibody (PACO12986)
Antibody SKU:PACO12986
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human TUBB2B
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.320°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity Purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:50kd;
UniProt Protein Function:TUBB2B: Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. TUBB2B is implicated in neuronal migration. Defects in TUBB2B are a cause of polymicrogyria asymmetric (PMGA). PMGA is a malformation of the cortex in which the brain surface is irregular and characterized by an excessive number of small gyri with abnormal lamination. Belongs to the tubulin family.
UniProt Protein Details:

Protein type:Cytoskeletal

Chromosomal Location of Human Ortholog: 6p25

Cellular Component: microtubule; nucleus

Molecular Function:protein binding

Biological Process: neuron migration

Disease: Polymicrogyria, Symmetric Or Asymmetric

NCBI Summary:The protein encoded by this gene is a beta isoform of tubulin, which binds GTP and is a major component of microtubules. This gene is highly similar to TUBB2A and TUBB2C. Defects in this gene are a cause of asymmetric polymicrogyria. [provided by RefSeq, Mar 2010]
UniProt Code:Q9BVA1
NCBI GenInfo Identifier:74761283
NCBI Gene ID:347733
NCBI Accession:Q9BVA1.1
UniProt Secondary Accession:Q9BVA1,A8K068,
UniProt Related Accession:Q9BVA1
Molecular Weight:49,953 Da
NCBI Full Name:Tubulin beta-2B chain
NCBI Synonym Full Names:tubulin beta 2B class IIb
NCBI Official Symbol:TUBB2B  
NCBI Official Synonym Symbols:PMGYSA; bA506K6.1  
NCBI Protein Information:tubulin beta-2B chain
UniProt Protein Name:Tubulin beta-2B chain
Protein Family:Tubulin
UniProt Gene Name:TUBB2B  
UniProt Entry Name:TBB2B_HUMAN

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