The TPD52L2 Antibody (PAC020740) is a polyclonal antibody designed for research involving TPD52L2, a protein encoded by the TPD52L2 gene. This antibody, raised in rabbits, is highly specific and reactive with human samples, making it an excellent tool for studies in cell biology and cancer research. TPD52L2 is a member of the Tumor Protein D52 (TPD52) family and has been implicated in various cellular processes, including cell proliferation, migration, and apoptosis. It has also been linked to cancer progression and metastasis, with overexpression observed in multiple cancer types.
The TPD52L2 Antibody enables the detection and analysis of TPD52L2 protein expression in various cell types, providing valuable insights into its role in cellular physiology and tumorigenesis. Its validation for use in Western blot applications makes it a versatile tool for researchers interested in exploring the function and potential therapeutic targeting of TPD52L2 in cancer and other diseases.
The image on the left is immunohistochemistry of paraffin-embedded Human breast cancer tissue using PACO20740(TPD52L2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
Gel: 8%SDS-PAGE, Lysate: 40 µg, Lane 1-5: 293T cells, MCF7 cells, mouse brain tissue, K562 cells, mouse bladder tissue, Primary antibody: PACO20740(TPD52L2 Antibody) at dilution 1/400, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 20 seconds.
The image on the left is immunohistochemistry of paraffin-embedded Human liver cancer tissue using PACO20740(TPD52L2 Antibody) at dilution 1/35, on the right is treated with synthetic peptide. (Original magnification: x200).
Background:
This gene encodes a member of the tumor protein D52-like family. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. Expression of this gene may be a marker for breast cancer and acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 12.
Synonyms:
tumor protein D52-like 2
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This gene encodes a member of the tumor protein D52-like family. These proteins are characterized by an N-terminal coiled-coil motif that is used to form homo- and heteromeric complexes with other tumor protein D52-like proteins. Expression of this gene may be a marker for breast cancer and acute lymphoblastic leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 12. [provided by RefSeq, Aug 2011]
