TIN2/TINF2 Rabbit Polyclonal Antibody (CAB6769)
- SKU:
- CAB6769
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | TIN2/TINF2 Rabbit Polyclonal Antibody |
SKU: | CAB6769 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 202-451 of human TIN2/TIN2/TINF2 (NP_001092744.1). |
Sequence: | ECSV TDSV NLAE PMEQ NPPQ QQRL ALHN PLPK AKPG THLP QGPS SRTH PEPL AGRH FNLA PLGR RRVQ SQWA STRG GHKE RPTV MLFP FRNL GSPT QVIS KPES KEEH AIYT ADLA MGTR AAST GKSK SPCQ TLGG RALK ENPV DLPA TEQK ENCL DCYM DPLR LSLL PPRA RKPV CPPS LCSS VITI GDLV LDSD EEEN GQGE GKES LENY QKTK FDTL IPTL CEYL PPSG HGAI PVSS CDCR DSSR PL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | TIN2; DKCA3; TIN2/TINF2 |
Positive Sample: | MCF7,HepG2,Mouse skeletal muscle,Mouse heart |
Conjugate: | Unconjugated |
Cellular Localization: | Chromosome, Nucleus, Nucleus matrix, telomere. |
Calculated MW: | 50kDa |
Observed MW: | 40-45kDa |
This gene encodes one of the proteins of the shelterin, or telosome, complex which protects telomeres by allowing the cell to distinguish between telomeres and regions of DNA damage. The protein encoded by this gene is a critical part of shelterin; it interacts with the three DNA-binding proteins of the shelterin complex, and it is important for assembly of the complex. Mutations in this gene cause dyskeratosis congenita (DKC), an inherited bone marrow failure syndrome.
Purification Method: | Affinity purification |
Gene ID: | 26277 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |