Based on the information provided in the URL, the TIMM10B Polyclonal Antibody (CAB8488) is a valuable tool for research involving TIMM10B, a protein responsible for translocating precursor proteins into mitochondria. This antibody, produced in rabbits, demonstrates high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the TIMM10B protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in mitochondrial biology and cellular metabolism.TIMM10B plays a crucial role in protein import into mitochondria, a process essential for mitochondrial function and cellular energy production.
Dysregulation of TIMM10B has been linked to mitochondrial dysfunction and various mitochondrial-related disorders. By studying the expression and function of TIMM10B, researchers can gain insights into the molecular mechanisms underlying mitochondrial protein import and its implications for human health.Overall, the TIMM10B Polyclonal Antibody offers researchers a reliable tool for investigating the role of TIMM10B in mitochondrial biology and related diseases. Its high specificity and reactivity make it a valuable asset for research in fields such as biochemistry, molecular biology, and mitochondrial physiology.
Product Name:
TIMM10B Rabbit Polyclonal Antibody
SKU:
CAB8488
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-103 of human TIMM10B (NP_036324.1).
FXC1, or TIMM10B, belongs to a family of evolutionarily conserved proteins that are organized in heterooligomeric complexes in the mitochondrial intermembrane space. These proteins mediate the import and insertion of hydrophobic membrane proteins into the mitochondrial inner membrane.
Purification Method:
Affinity purification
Gene ID:
26515
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using TIMM10B Rabbit pAb (CAB8488) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
