The TFAM Rabbit Monoclonal Antibody (CAB3173) is a highly specific antibody designed for research involving TFAM, a key regulator of mitochondrial DNA transcription and maintenance. This antibody, produced in rabbits, is suitable for use in various applications such as immunofluorescence, immunoprecipitation, and flow cytometry.TFAM, also known as mitochondrial transcription factor A, plays a crucial role in the replication and transcription of mitochondrial DNA, making it essential for mitochondrial function and biogenesis. Dysregulation of TFAM has been implicated in various diseases including neurodegenerative disorders, metabolic diseases, and cancer.
Therefore, studying the expression and function of TFAM is essential for understanding the role of mitochondria in health and disease.The TFAM Rabbit Monoclonal Antibody (CAB3173) offers high specificity and sensitivity, enabling researchers to accurately detect and analyze TFAM in various samples. Its versatility and reliability make it an invaluable tool for studies focusing on mitochondrial biology, metabolism, and disease mechanisms. Order now and advance your research in this crucial area of study.
Product Name:
TFAM Rabbit Monoclonal Antibody
SKU:
CAB3173
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human TFAM (NP_003192.1).
This gene encodes a key mitochondrial transcription factor containing two high mobility group motifs. The encoded protein also functions in mitochondrial DNA replication and repair. Sequence polymorphisms in this gene are associated with Alzheimer's and Parkinson's diseases. There are pseudogenes for this gene on chromosomes 6, 7, and 11. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
7019
Clone Number:
ARC51776
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using TFAM Rabbit pAb (CAB3173) at 1:1200 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
