The TBX22 Polyclonal Antibody (CAB7801) is a powerful tool for researchers studying TBX22, a transcription factor essential for normal development of the palate and teeth. This antibody, produced using rabbits as a host, exhibits high reactivity with human samples and is validated for use in Western blot applications. It specifically targets the TBX22 protein, allowing for precise detection and analysis across a variety of cell types.
TBX22 plays a crucial role in craniofacial development and is implicated in conditions such as cleft palate and tooth abnormalities. By studying TBX22 expression and function, researchers can gain insights into the molecular mechanisms underlying these developmental disorders. The TBX22 Polyclonal Antibody is an invaluable tool for investigations in developmental biology, genetic disorders, and oral health research.
Product Name:
TBX22 Rabbit Polyclonal Antibody
SKU:
CAB7801
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 291-520 of human TBX22 (NP_058650.1).
This gene is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. Mutations in this gene have been associated with the inherited X-linked disorder, Cleft palate with ankyloglossia, and it is believed to play a major role in human palatogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
50945
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using TBX22 antibody (CAB7801) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
