The TBX20 Polyclonal Antibody (CAB15994) is a valuable tool for researchers studying the TBX20 transcription factor, known for its role in heart development and function. This antibody, generated in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to the TBX20 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for studies in cardiovascular biology and regenerative medicine.TBX20 is a crucial regulator of heart formation and cardiac function, with mutations in the TBX20 gene being associated with congenital heart defects and cardiomyopathy.
Understanding the mechanisms by which TBX20 controls cardiac development and function is essential for advancing our knowledge of heart disease and potentially identifying new therapeutic targets. The TBX20 Polyclonal Antibody provides researchers with a reliable tool for investigating the functions of TBX20 in both normal and diseased hearts, paving the way for advancements in cardiovascular research.
Product Name:
TBX20 Rabbit Polyclonal Antibody
SKU:
CAB15994
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-290 of human TBX20 (NP_001071121.1).
This gene encodes a T-box family member. The T-box family members share a common DNA binding domain, termed the T-box, and they are transcription factors involved in the regulation of developmental processes. This gene is essential for heart development. Mutations in this gene are associated with diverse cardiac pathologies, including defects in septation, valvulogenesis and cardiomyopathy. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
57057
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from Rat heart, using TBX20 Rabbit pAb (CAB15994) at 1:900 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
