The TBCC Polyclonal Antibody (CAB17537) is a valuable tool for researchers studying the TBCC protein, which plays a critical role in cellular processes such as microtubule formation and organization. Raised in rabbits, this antibody is highly reactive with human samples and has been validated for use in Western blot applications.TBCC, also known as Tubulin-specific Chaperone C, is essential for the proper assembly and function of microtubules, which are involved in various cellular functions such as cell division, intracellular transport, and cell shape maintenance.
Dysregulation of TBCC has been implicated in diseases such as cancer, neurodegenerative disorders, and developmental abnormalities.By using the TBCC Polyclonal Antibody, researchers can detect and analyze TBCC protein expression in different cell types, allowing for a better understanding of its role in cellular processes and its potential implications in disease. This antibody is an invaluable tool for studies in cell biology, cancer research, and developmental biology.
Product Name:
TBCC Rabbit Polyclonal Antibody
SKU:
CAB17537
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-346 of human TBCC (NP_003183.1).
Cofactor C is one of four proteins (cofactors A, D, E, and C) involved in the pathway leading to correctly folded beta-tubulin from folding intermediates. Cofactors A and D are believed to play a role in capturing and stabilizing beta-tubulin intermediates in a quasi-native confirmation. Cofactor E binds to the cofactor D/beta-tubulin complex; interaction with cofactor C then causes the release of beta-tubulin polypeptides that are committed to the native state.
Purification Method:
Affinity purification
Gene ID:
6903
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using TBCC Rabbit pAb (CAB17537) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
