The SULT1C4 Polyclonal Antibody (CAB15433) is a valuable tool for researchers studying SULT1C4, a member of the sulfotransferase family involved in the metabolism of various endogenous compounds and xenobiotics. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.SULT1C4 plays a crucial role in detoxification processes by catalyzing the sulfation of a wide range of substrates, including hormones, neurotransmitters, and drugs. Its expression levels and activity are associated with drug metabolism, hormone regulation, and detoxification pathways in the body. The SULT1C4 Polyclonal Antibody enables the detection and analysis of SULT1C4 protein levels in different cell types, providing insights into its function and potential implications in drug metabolism and disease states.
Research involving SULT1C4 is important for understanding its role in the body's detoxification processes, as well as its potential impact on drug efficacy and toxicity. By studying SULT1C4 expression and activity, researchers can gain valuable insights into how this enzyme contributes to overall health and disease susceptibility, paving the way for the development of personalized medicine approaches and novel therapeutic strategies.
Product Name:
SULT1C4 Rabbit Polyclonal Antibody
SKU:
CAB15433
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-95 of human SULT1C4 (NP_006579.2).
Sulfotransferase enzymes catalyze the sulfate conjugation of many hormones, neurotransmitters, drugs, and xenobiotic compounds. These cytosolic enzymes are different in their tissue distributions and substrate specificities. The gene structure (number and length of exons) is similar among family members. This gene encodes a protein that belongs to the SULT1 subfamily, responsible for transferring a sulfo moiety from PAPS to phenol-containing compounds.
Purification Method:
Affinity purification
Gene ID:
27233
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SULT1C4 Rabbit pAb (CAB15433) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 2s.
