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SSU72 Monoclonal Antibody [PAT66D10AT] (CPAB0261)

SKU:
CPAB0261
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT66D10AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

SSU72 Monoclonal Antibody [PAT66D10AT] (CPAB0261)

The SSU72 Polyclonal Antibody (CPAB0261) is a valuable tool for researchers studying SSU72, a key regulatory protein involved in RNA processing and transcription. This antibody, generated in rabbits, displays high reactivity specifically with human samples and has been validated for use in Western blot applications. By binding to SSU72 protein, this antibody enables precise detection and analysis, making it an essential component for studies in molecular biology and gene expression.SSU72 is essential for the proper functioning of the RNA polymerase II complex and is involved in the cleavage and polyadenylation process of mRNA synthesis.

Its role in transcription regulation makes it a crucial target for research in various fields, including cancer biology, developmental biology, and gene expression studies. Understanding the function and regulation of SSU72 is vital for uncovering its impact on cellular processes and disease mechanisms, providing insights for potential therapeutic interventions.

Product Name:SSU72 Antibody
Product Sku:CPAB0261
Size:5μg
Host Species:Mouse
Immunogen:Anti-human SSU72 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human SSU72 amino acids 1-194 purified from Ecoli.
Clone:PAT66D10AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:SSU72 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:SSU72 is an extremely conserved homologue of yeast Ssu72, a CTD phosphatase and a component of the polyadenylation/termination machinery. SSU72 interacts with TFIIB, Rb and DNAM-1 and operates to catalyze the dephosphorylation of target proteins, and taking part in RNA processing and termination via dephosphorylation of Pol II. SSU72 is found in multiple alternatively spliced isoforms.
Synonyms:SSU72 RNA polymerase II CTD phosphatase homolog (S. cerevisiae), HSPC182, CTD phosphatase SSU72, Ssu72 RNA polymerase II CTD phosphatase homolog (yeast), PNAS-120, RNA polymerase II subunit A C-terminal domain phosphatase SSU72, EC 3.1.3.16.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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