The SLCO6A1 Polyclonal Antibody (CAB14963) is a valuable tool for researchers studying SLCO6A1, a solute carrier protein associated with drug transport and metabolism. This rabbit-derived antibody has been validated for use in various immunoassays, including Western blotting, immunofluorescence, and immunohistochemistry. By specifically targeting the SLCO6A1 protein, this antibody allows for accurate detection and analysis in a variety of cell types and tissue samples.SLCO6A1 is known to play a crucial role in the transport of endogenous substances and drugs across cell membranes, making it a key player in drug pharmacokinetics and pharmacodynamics.
Understanding the expression and function of SLCO6A1 is important for researchers studying drug transport, drug-drug interactions, and personalized medicine approaches.With its high reactivity and specificity for human samples, the SLCO6A1 Polyclonal Antibody is a valuable tool for researchers in the fields of pharmacology, toxicology, and drug development. Its ability to accurately detect and analyze SLCO6A1 protein expression makes it an essential component of studies aimed at understanding drug transport mechanisms and improving therapeutic outcomes.
Product Name:
SLCO6A1 Rabbit Polyclonal Antibody
SKU:
CAB14963
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 480-580 of human SLCO6A1 (NP_775759.3).
Sequence:
VQFA GINE DYDG TGKL GNLT APCN EKCR CSSS IYSS ICGR DDIE YFSP CFAG CTYS KAQN QKKM YYNC SCIK EGLI TADA EGDF IDAR PGKC DAKC YKLP L
Tested Applications:
WBELISA
Recommended Dilution:
WB,1:500 - 1:2000
Synonyms:
GST; CT48; OATPY; OATP-I; OATP6A1; SLCO6A1
Positive Sample:
SH-SY5Y,293T,A-549,NCI-H460,Mouse brain
Conjugate:
Unconjugated
Cellular Localization:
Cell membrane, Multi-pass membrane protein.
Calculated MW:
79kDa
Observed MW:
80kDa
Predicted to enable sodium-independent organic anion transmembrane transporter activity. Predicted to be involved in sodium-independent organic anion transport. Predicted to be located in plasma membrane. Predicted to be integral component of membrane. Predicted to be integral component of plasma membrane.
Purification Method:
Affinity purification
Gene ID:
133482
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLCO6A1 Rabbit pAb (CAB14963) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
