The SLC6A8 Polyclonal Antibody (CAB17531) offered by Assay Genie is a valuable tool for researchers studying the SLC6A8 protein, which is involved in the transport of creatine in cells. This rabbit-derived antibody has been extensively validated for use in Western blot applications and is highly reactive with human samples, allowing for accurate detection and analysis of SLC6A8 protein levels.SLC6A8, also known as the creatine transporter, plays a crucial role in cellular energy metabolism by facilitating the uptake of creatine, an important molecule for muscle function and brain health.
Dysregulation of SLC6A8 has been implicated in various disorders, including creatine deficiency syndromes and neurological conditions.By using the SLC6A8 Polyclonal Antibody, researchers can gain insight into the expression and function of SLC6A8 in different cell types and tissues, advancing our understanding of its role in health and disease. This antibody is a valuable tool for studies in metabolism, neuroscience, and genetics, providing valuable data for potential therapeutic interventions targeting SLC6A8-related disorders.
Product Name:
SLC6A8 Rabbit Polyclonal Antibody
SKU:
CAB17531
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 539-635 of human SLC6A8 (NP_005620.1).
The protein encoded by this gene is a plasma membrane protein whose function is to transport creatine into and out of cells. Defects in this gene can result in X-linked creatine deficiency syndrome. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6535
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using SLC6A8 Rabbit pAb (CAB17531) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
