The SLC25A13 Polyclonal Antibody (CAB5849) is specifically designed for research involving SLC25A13, a key mitochondrial solute carrier protein involved in the transport of citrate across the mitochondrial inner membrane. The antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding to the SLC25A13 protein, this antibody enables accurate detection and analysis in various cell types, making it an essential tool for studies in metabolism, mitochondrial function, and metabolic disorders.SLC25A13 plays a crucial role in citrate metabolism and the regulation of cellular energy production, making it a target of interest in research related to metabolic diseases, obesity, and diabetes.
Understanding the function and regulation of SLC25A13 is essential for unraveling the complex mechanisms underlying metabolic disorders and developing targeted therapies to address these conditions. The SLC25A13 Polyclonal Antibody provides researchers with a reliable tool for investigating the role of SLC25A13 in health and disease, paving the way for advancements in metabolic research.
Product Name:
SLC25A13 Polyclonal Antibody
SKU:
CAB5849
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human SLC25A13 (NP_001153682.1).
This gene is a member of the mitochondrial carrier family. The encoded protein contains four EF-hand Ca(2+) binding motifs in the N-terminal domain, and localizes to mitochondria. The protein catalyzes the exchange of aspartate for glutamate and a proton across the inner mitochondrial membrane, and is stimulated by calcium on the external side of the inner mitochondrial membrane. Mutations in this gene result in citrullinemia, type II. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
10165
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates, using SLC25A13 Rabbit pAb (CAB5849) at 1:400 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
