The SGK1 Rabbit Monoclonal Antibody (CAB3936) is a valuable tool for researchers studying SGK1, a key enzyme involved in cell growth, survival, and metabolism regulation. This highly specific antibody, generated in rabbits, is ideal for detecting SGK1 protein in human samples and is validated for use in Western blot applications. By binding to SGK1, this antibody allows for precise detection and analysis of SGK1 levels in various cell types, making it essential for studies in molecular biology and cancer research.SGK1, a member of the Serine/Threonine protein kinase family, is known for its role in numerous cellular processes such as cell proliferation, survival, and ion transport.
Its dysregulation has been implicated in cancer development and progression, making it a promising target for therapeutic interventions. Research on SGK1 is essential for understanding its molecular mechanisms and exploring its potential as a biomarker or therapeutic target in cancer and other diseases.Overall, the SGK1 Rabbit Monoclonal Antibody (CAB3936) is a high-quality research tool that enables precise and reliable detection of SGK1 protein, making it indispensable for scientists investigating the role of SGK1 in cellular physiology and disease pathology.
Product Name:
SGK1 Rabbit Monoclonal Antibody
SKU:
CAB3936
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-100 of human SGK1 (O00141).
This gene encodes a serine/threonine protein kinase that plays an important role in cellular stress response. This kinase activates certain potassium, sodium, and chloride channels, suggesting an involvement in the regulation of processes such as cell survival, neuronal excitability, and renal sodium excretion. High levels of expression of this gene may contribute to conditions such as hypertension and diabetic nephropathy. Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Purification Method:
Affinity purification
Gene ID:
6446
Clone Number:
ARC0868
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using SGK1 Rabbit mAb (CAB3936) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3min.
