null

SARS Nucleocapsid PT3851 [PT3851] (CPAB0421)

SKU:
CPAB0421
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Virus
Host Species:
Rabbit
Isotype:
IgG
€2,079
Frequently bought together:

Description

system_update_alt Datasheet

SARS Nucleocapsid PT3851 [PT3851] (CPAB0421)

The SARS Nucleocapsid Polyclonal Antibody (PT3851) is a valuable tool for researchers studying the SARS virus and its nucleocapsid protein. This antibody, produced in rabbits, is highly specific and reactive with SARS nucleocapsid protein in human samples. It has been validated for use in various applications, including Western blotting, immunofluorescence, and ELISA.The SARS nucleocapsid protein is essential for viral RNA packaging and replication, making it a key target for antiviral drug development and vaccine research.

By using the PT3851 antibody, researchers can accurately detect and study the SARS virus in infected cells and tissues. This antibody is a valuable asset for understanding the biology of the SARS virus and developing strategies for combating future outbreaks.

Product Name:SARS Nucleocapsid PT3851
Product Sku:CPAB0421
Size:100μg
Host Species:
Immunogen:Recombinant protein fragment 1-49 a.aof the SARS nucleoprotein.
Clone:PT3851
Reactivity:Viral
Applications:ELISA
Purification Method:Protein A affinity purified.
Isotype:
Background:SARS Coronavirus is an enveloped virus containing three outer structural proteins, namely the membrane (M), envelope (E), and spike (S) proteins. Spike (S)-glycoprotein of the virus interacts with a cellular receptor and mediates membrane fusion to allow viral entry into susceptible target cells. Accordingly, S-protein plays an important role in virus infection cycle and is the primary target of neutralizing antibodies.It has recently been shown that SARS is caused by a human coronavirus. Human coronaviruses are the major cause of upper respiratory tract illness in humans, such as the common cold. Coronaviruses are positive-stranded RNA viruses, featuring the largest viral RNA genomes known to date (27-31 kb). The first step in coronavirus infection is binding of the viral spike protein, a 139-kDa protein, to certain receptors on host cells. The spike protein is the main surface antigen of the coronavirus. The most prominent protein in the culture supernatants infected with SARS virus is a 46 kDa nucleocapsid protein. This suggests that the nucleocapsid protein is a major immunogen that may be useful for early diagnostics.
Synonyms:
Storage Buffer:

Related Products