RUNX1 Polyclonal Antibody (CAB24747)
- SKU:
- CAB24747
Frequently bought together:
Description
| Product Name: | RUNX1 Polyclonal Antibody |
| SKU: | CAB24747 |
| Size: | 100uL |
| Isotype: | IgG |
| Host Species: | Rabbit |
| Reactivity: | Human,Mouse |
| Immunogen: | KLH-conjugated synthetic peptide encompassing a sequence within the center region of human RUNX1. |
| Tested Applications: | WB |
| Recommended Dilution: | WB,1:500 - 1:1000 |
| Synonyms: | AML1; CBFA2; EVI-1; AMLCR1; PEBP2aB; CBF2alpha; AML1-EVI-1; PEBP2alpha; RUNX1 |
| Positive Sample: | Jurkat,Mouse thymus |
| Conjugate: | Unconjugated |
| Cellular Localization: | Nucleus. |
| Calculated MW: | 49kDa |
| Observed MW: | 55kDa |
Core binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well-documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have been found for this gene.
| Purification Method: | Affinity purification |
| Gene ID: | 861 |
| Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates using RUNX1 Rabbit pAb (CAB24747) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25 μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Negative control (NC): SH-SY5Y.Exposure time: 60s. |
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