The RNH1 Polyclonal Antibody (CAB4079) is a valuable tool for researchers studying RNH1, a ribonuclease protein involved in RNA processing and regulation. This high-quality antibody is produced in rabbits and exhibits strong reactivity with human samples, making it ideal for a variety of research applications.RNH1 is known to play a crucial role in maintaining RNA integrity and stability within the cell. Dysregulation of RNH1 has been linked to various diseases, including cancer and neurodegenerative disorders. By using the RNH1 Polyclonal Antibody, researchers can accurately detect and analyze the expression of RNH1 in different cell types and tissues.
With its validated performance in Western blotting, this antibody enables precise detection of RNH1 protein levels, facilitating in-depth studies on the function and regulation of RNH1 in various cellular processes. Researchers in the fields of molecular biology, biochemistry, and oncology can benefit from the insights gained through the use of this antibody in their experiments.
Product Name:
RNH1 Rabbit Polyclonal Antibody
SKU:
CAB4079
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 202-461 of human RNH1 (NP_002930.2).
Placental ribonuclease inhibitor (PRI) is a member of a family of proteinaceous cytoplasmic RNase inhibitors that occur in many tissues and bind to both intracellular and extracellular RNases (summarized by Lee et al., 1988 [PubMed 3219362]). In addition to control of intracellular RNases, the inhibitor may have a role in the regulation of angiogenin (MIM 105850). Ribonuclease inhibitor, of 50,000 Da, binds to ribonucleases and holds them in a latent form. Since neutral and alkaline ribonucleases probably play a critical role in the turnover of RNA in eukaryotic cells, RNH may be essential for control of mRNA turnover; the interaction of eukaryotic cells with ribonuclease may be reversible in vivo.
Purification Method:
Affinity purification
Gene ID:
6050
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using RNH1 antibody (CAB4079) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
