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RELA Polyclonal Antibody (CAB22684)

SKU:
CAB22684
Product Type:
Antibody
Antibody Type:
Polyclonal Antibody
Reactivity:
Human
Host Species:
Rabbit
Isotype:
IgG
Applications:
WB
$167 - $635
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Description

system_update_altDatasheetsystem_update_altMSDS
Product Name:RELA Polyclonal Antibody
SKU:CAB22684
Size:20uL, 100uL
Isotype:IgG
Host Species:Rabbit
Reactivity:Human
Immunogen:Recombinant protein of mouse RELA.
Tested Applications:WB ELISA
Recommended Dilution:WB,1:500 - 1:1000
Synonyms:p65; p65 NFkB; p65 NF-kappa B; LA
Positive Sample:HeLa
Conjugate:Unconjugated
Cellular Localization:cytoplasm, cytosol, glutamatergic synapse, nucleus
Calculated MW:60kDa
Observed MW:65kDa

Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; actinin binding activity; and ankyrin repeat binding activity. Involved in several processes, including negative regulation of protein sumoylation; postsynapse to nucleus signaling pathway; and regulation of transcription, DNA-templated. Acts upstream of or within several processes, including cellular response to hepatocyte growth factor stimulus; cellular response to lipopolysaccharide; and positive regulation of interleukin-12 production. Located in several cellular components, including chromatin; cytosol; and glutamatergic synapse. Is expressed in several structures, including alimentary system; early conceptus; genitourinary system; musculature; and skin. Human ortholog(s) of this gene implicated in ductal carcinoma in situ; lung non-small cell carcinoma; lymphoma; and renal cell carcinoma. Orthologous to human RELA (RELA proto-oncogene, NF-kB subunit).

Purification Method:Affinity purification
Gene ID:19697
Storage Buffer:Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Product ImageWestern blot analysis of extracts from wild type(WT) and RELA knockout (KO) HeLa cells, using RELA Rabbit pAb antibody (CAB22684) at 1:700 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.

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