Recombinant Mouse SIRP-alpha/CD172a Protein (RPCB1646)
- SKU:
- RPCB1646
- Size:
- 10µg
- Tag:
- C-hFC
- Reactivity:
- Mouse
- Expression Host:
- HEK293 cells
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Description
| Product Name: | Recombinant Mouse SIRP-alpha/CD172a Protein |
| SKU: | RPCB1646 |
| Size: | 10µg |
| Tag: | C-hFC |
| Reactivity: | Mouse |
| Expression Host: | HEK293 cells |
| Protein Description: | High quality, high purity and low endotoxin recombinant Recombinant Mouse SIRP-alpha/CD172a Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed. |
| Endotoxin: | <0.1EU/μg |
| Purity: | > 95% by SDS-PAGE. |
| Formulation: | Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4. |
| Gene ID: | 19261 |
Signal regulatory protein α (SIRPα) is a regulatory membrane glycoprotein from SIRP family expressed mainly by myeloid cells and also by stem cells or neurons.SIRPα acts as inhibitory receptor and interacts with a broadly expressed transmembrane protein CD47 also called the "don′t eat me" signal.Cancer cells highly expressed CD47 that activate SIRP α and inhibit macrophage-mediated destruction.
| Storage: | Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week. |
| Reconstitution: | Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles. |
| Swiss-Prot: | P97797 |
 | Recombinant Mouse SIRP- alpha/CD172a Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 100-120 kDa. |
 | Immobilized Human CD47 at 2 μg/mL (100 μL/well) can bind Mouse CD172a with a linear range of 1.2-55.3 ng/mL. |
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