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Recombinant Human IL-17RA/CD217 Protein (RPCB0414)

SKU:
RPCB0414
Size:
10µg
Tag:
C-His
Reactivity:
Human
Expression Host:
HEK293 cells
€69
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Description

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Product Name:Recombinant Human IL-17RA/CD217 Protein
SKU:RPCB0414
Size:10µg
Tag:C-His
Reactivity:Human
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human IL-17RA/CD217 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:< 0.1 EU/μg of the protein by LAL method.
Purity:> 95% by SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.Contact us for customized product form or formulation.
Gene ID:23765

Interleukin 17A (IL17A) is a proinflammatory cytokine secreted by activated T-lymphocytes. It is a potent inducer of the maturation of CD34-positive hematopoietic precursors into neutrophils. This transmembrane protein (interleukin 17A receptor; IL17RA) is a ubiquitous type I membrane glycoprotein that binds with low affinity to interleukin 17A. Interleukin 17A and its receptor play a pathogenic role in many inflammatory and autoimmune diseases such as rheumatoid arthritis. Like other cytokine receptors, this receptor likely has a multimeric structure.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:Q96F46
Product ImageRecombinant Human IL-17RA/CD217 Protein was determined by SDS- PAGE with Coomassie Blue, showing a band at 55-65 kDa.
Product ImageRecombinant Human IL17RA inhibits IL-17A induced IL-6 secretion by Hela cells. The ED₅₀ for this effect is 0.02_x0000_0.1 µg/mL in the presence of 10 ng/mL recombinant human IL-17A.

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