Immunoglobulin superfamily member 11(IGSF11) are expressed on the plasma membrane in the tesis and brain. These IGSF proteins undergo final modifications during capacitation and/or the acrosome reaction. IGSF proteins share significant homology with endothelial cell-selective adhesion molecule and coxsackievirus and adenovirus receptor, which mediates cell attachment and homotypic intercellular interactions. In clinical, the IGSF11 has been reported to over expressed in colorectal cancers and hepatocellular carcinomas as well as intestinal-type gastric cancers compared to their corresponding non- cancerous tissues. The IGSF11 has also been found expressed abundantly in testis and ovary and the IGSF11 can be used as a candidate of cancer-testis antigen.
Product Name:
Human IGSF11/BTIGSF Recombinant Protein (RPES4550)
Product Code:
RPES4550
Size:
20µg
Species:
Human
Expressed Host:
HEK293 Cells
Synonyms:
BT-IgSF, CT119, CXADRL1, Igsf13, VSIG3, CXADR like 1
Accession:
AAH34411.1
Sequence:
Met 1-Gly 240
Fusion tag:
C-His
Endotoxin:
<1.0 EU per µg as determined by the LAL method.
Protein Construction:
A DNA sequence encoding the extracellular domain of human IGSF11 (AAH34411.1) (Met 1-Gly 240) was fused with a polyhistidine tag at the C-terminus
Purity:
> 85 % as determined by reducing SDS-PAGE.
Mol Mass:
24.6 kDa
AP Mol Mass:
36 kDa
Formulation:
Lyophilized from sterile PBS, pH 7.4
Shipping:
This product is provided as lyophilized powder which is shipped with ice packs.
Stability and Storage:
Lyophilized proteins are stable for up to 12 months when stored at -20 to -80°C. Reconstituted protein solution can be stored at 4-8°C for 2-7 days. Aliquots of reconstituted samples are stable at < -20°C for 3 months.
