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Recombinant Human ERAP2 Protein (RPCB1946)

SKU:
RPCB1946
Size:
50µg
Tag:
N-His
Reactivity:
Human
Expression Host:
HEK293 cells
€759
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Description

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Product Name:Recombinant Human ERAP2 Protein
SKU:RPCB1946
Size:50µg
Tag:N-His
Reactivity:Human
Expression Host:HEK293 cells
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human ERAP2 Protein , tested reactivity in HEK293 cells and has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:< 1 EU/μg of the protein by LAL method.
Purity:> 95% by SDS-PAGE.
Formulation:Supplied as a 0.22 μm filtered solution in 12.5mM Tris, 75mM NaCl, pH 7.5, 50% glycercol. Contact us for customized product form or formulation.
Gene ID:64167

Leukocyte-derived arginine aminopeptidase (LRAP), also known as endoplasmic reticulum-aminopeptidase 2 (ERAP2), is the second identified aminopeptidase localized in the in the lumenal side of endoplasmic reticulum (ER) processing antigenic peptides presented to major histocompatibility complex (MHC) class I molecules. It is a 96-amino acid protein with significant homology to placental leucine aminopeptidase and adipocyte-derived leucine aminopeptidase. LRAP preferentially hydrolyzes the basic residues Arg and Lys, and contains the HEXXH(X)18E zinc-binding motif, which is the characteristic of the M1 family of zinc metallopeptidases which also includes PILS/ARTS1/ERAP1 and LNPEP/PLAP. Induced by interferon-gamma, LRAP is able to trim various MHC class I antigenic peptide precursors.

Storage:Store at -70℃. This product is stable at ≤ -70℃ for up to 1 year from the date of receipt. For optimal storage, aliquot into smaller quantities after centrifugation and store at recommended temperature. Avoid repeated freeze-thaw cycles.
Swiss-Prot:Q6P179
Product ImageRecombinant Human ERAP2 Protein was determined by SDS-PAGE with Coomassie Blue, showing a band at 115-125 kDa.

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