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Recombinant Human CCL2/MCP-1 Protein (RPCB1717)

SKU:
RPCB1717
Size:
10µg
Tag:
NO-tag
Reactivity:
Human
Expression Host:
Pichia
$167
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Description

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Product Name:Recombinant Human CCL2/MCP-1 Protein
SKU:RPCB1717
Size:10µg
Tag:NO-tag
Reactivity:Human
Expression Host:Pichia
Protein Description:High quality, high purity and low endotoxin recombinant Recombinant Human CCL2/MCP-1 Protein , tested reactivity inPichiaand has been validated in SDS-PAGE.100% guaranteed.
Endotoxin:<0.1EU/μg
Purity:> 95% by SDS-PAGE.
Formulation:Lyophilized from a 0.22 μm filtered solution of PBS, pH 7.4.
Gene ID:6347

Monokine with inflammatory and chemokinetic properties. Binds to CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.

Storage:Store at -20℃.Store the lyophilized protein at -20℃ to -80 ℃ up to 1 year from the date of receipt.After reconstitution, the protein solution is stable at -20℃ for 3 months, at 2-8℃ for up to 1 week.
Reconstitution:Centrifuge the vial before opening. Reconstitute to a concentration of 0.1-0.5 mg/mL in sterile distilled water. Avoid vortex or vigorously pipetting the protein. For long term storage, it is recommended to add a carrier protein or stablizer (e.g. 0.1% BSA, 5% HSA, 10% FBS or 5% Trehalose), and aliquot the reconstituted protein solution to minimize free-thaw cycles.
Swiss-Prot:P13500
Product ImageRecombinant Human CCL2/MCP-1 Protein was determined by SDS- PAGE with Coomassie Blue, showing a band at 10-15 kDa. Recombinant Human CCL2/MCP-1 chemoattract THP-1 cells. The EDâ‚…â‚€ for this effect is typically 13.56-54.24 ng/mL.
Product ImageRecombinant Human CCL2/MCP-1 chemoattract THP-1 cells. The EDâ‚…â‚€ for this effect is typically 13.56-54.24 ng/mL.

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